Thelema Posted March 19, 2005 Does anyone know the metabolic pathway of DMT in the human brain? Obviously some I assume is metabolised to 5meo-DMT, but I think i remember reading somewhere that the main metabolite is 6meo-DMT. In particular I am trying to find out how the meatbolic byproducts of psilocin differ from the metabolic byproducts of DMT. I have a feeling that it is not merely a matter of increased latency of metabolism into 6meoDMT; that the byproducts from psilocin are somewhat different. There appears to be scant information about such things. Share this post Link to post Share on other sites
Torsten Posted March 19, 2005 why would the metabolite of psilocin be 6 substituted? shouldn't it be 4 substituted? Share this post Link to post Share on other sites
occidentalis Posted March 19, 2005 What are the primary chemical systems that metabolise tryptamines in the brain? MAO? Share this post Link to post Share on other sites
Auxin Posted March 19, 2005 Everywhere I look they talk about simple metabolism to IAA. Administration of DMT to rats/people/etc causing a drastic increase in IAA concentration in blood and urine. Is there evidence of methoxylation that I dont know about? Share this post Link to post Share on other sites
Amulte Posted March 19, 2005 it should be a 4 until it metabolites further and is discharge or stored. but there would be more metabolites as its a dense structure, but the compunds a simple. wheres my textbook gone? Share this post Link to post Share on other sites
Thelema Posted March 20, 2005 I WAS THINKING THat if DMT is converted to 6meoDMT then maybe 4HODMT is converted to DMT then 6meoDMT or, maybe forms a 4OH6meoDMT. IAA hey? thanks for that! Share this post Link to post Share on other sites
Tryptameanie Posted March 21, 2005 Heh heh. maybe you could piss on your cuttings to make them root. Pity it doesn't work the other way... Share this post Link to post Share on other sites
psybernaut Posted March 21, 2005 Tryptameanie: Heh heh. maybe you could piss on your cuttings to make them root. Pity it doesn't work the other way... Root your cuttings to make them piss? :confused: Share this post Link to post Share on other sites