Took Galantamine last night

[Alchemist]

I've only had a handful of lucid dreams in my life and none for years. Last night I slept for about 4 hours and took a 4mg GalantamineHBr tablet for the first time ever. Went back to bed and fell asleep after what felt like 10 to 25 mins. And while dreaming became lucid! Incredible chemical this galantamine.

[Ishmael Fleishman]

Mind sharing were you source it from and what brand you used?

[Alchemist]

1 hour ago, Ishmael Fleishman said:

Mind sharing were you source it from and what brand you used?

Pm sent

Gonna try Huperzine A and DMAE over next few weeks as well.  

 

Can't say I have any good or bad side effects from it today.  

Edited March 7 by Alchemist

[Alchemist]

Quick update,  I've taken Galantamine 4mg three times now, and became lucid  twice. 

Also been trying Dimethylamimoethanol for 5 days, 50mg, but no luck. Also tried 200ug Huperizine A twice with no effect.

[Alchemist]

Galantamine is the real deal for lucid dreams. It worked again last night.

Unfortunately the more easily available huperizine A is useless for me. Took up to 400 mcg and simply felt weird the next day. 

DMAE , 50mg eq. freebase  for a week did nothing for dreams either.

Calea has done nothing in the past, but I never took it after sleeping for 4 hours first , like needs to be done for galantamine. So I will be giving that a go in a few days, after the G has cleared from the system.

 

[Alchemica]

On 29/03/2024 at 8:00 PM, Alchemist said:

Galantamine is the real deal for lucid dreams. It worked again last night.

Unfortunately the more easily available huperizine A is useless for me. Took up to 400 mcg and simply felt weird the next day. 

DMAE , 50mg eq. freebase  for a week did nothing for dreams either.

Calea has done nothing in the past, but I never took it after sleeping for 4 hours first , like needs to be done for galantamine. So I will be giving that a go in a few days, after the G has cleared from the system.

 

Galantamine is interesting as it functions as both an AChE inhibitor and positive allosteric modulator of a7-nAChRs, I found it quite cognitively  interesting but wasn't looking for lucid dreams. On the contrary, huperzine A seems more to be AChE/NMDARs.

 

Your DMAE dose seems personally quite low but I can see there being challenges using it with sleep as some people find it activating. As the bitartrate 250mg-500mg may be  more typical, eq, dimethylaminoethanol freebase ~186mg at the upper dose.

 

Out of interest, have you explored something like CDP-choline as a cholinergic? It seems to have procognitive effects mediated by predominately a7-nAChR  activation. More recently there's been interest in coupling AChE inhibition with CDP-choline or alpha-GPC for dementias and that seems to be an effective augmentation, so perhaps that could be possible to cautiously augment huperzine A with such, in theory.

 

I have some Silene undulata 98% triterpenoid saponins extract from the SAB store, if you want a bit in an envelope no cost send me a PM. It didn't get as frothy as expected (presumptive test for saponins) but did form a lasting sort of foam to some extent.

[Alchemist]

Quote

Galantamine is interesting as it functions as both an AChE inhibitor and positive allosteric modulator of a7-nAChRs, I found it quite cognitively  interesting but wasn't looking for lucid dreams. On the contrary, huperzine A seems more to be AChE/NMDARs.

 

Neuroscience is not my strength, would you say that  this difference  is a possible reason for galantamine being effective and the other not, although both increase the ACh in the brain?

I took 300ug of Huperizine A last night, this time before bed time, rather that after 4 hours of sleep, and all it did was to prevent me from sleeping. I though that perhaps it began to work at a slower pace than galantamine. I'm a bit disappointed as it is easily available and cheaper.

 

Quote

Your DMAE dose seems personally quite low but I can see there being challenges using it with sleep as some people find it activating. As the bitartrate 250mg-500mg may be  more typical, eq, dimethylaminoethanol freebase ~186mg at the upper dose.

 

I have suspended its use for now as I want to focus on one supplement at a time. The 50mg freebase was based on the journal article "Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams" by W. Sergio. He claimed that after 2 weeks, the level built up and he was able to have lucid dreams of the WILD type in the mornings. I will most definitely focus on this substance again in due course as it may have helped with my everyday memory.

 

Quote

Out of interest, have you explored something like CDP-choline as a cholinergic? It seems to have procognitive effects mediated by predominately a7-nAChR  activation. More recently there's been interest in coupling AChE inhibition with CDP-choline or alpha-GPC for dementias and that seems to be an effective augmentation, so perhaps that could be possible to cautiously augment huperzine A with such, in theory.

 

I haven't as yet, but I soon will receive alpha GPC, 600mg.  Apparently, it can also trigger lucidity by itself, according to the book "Advanced Lucid Dreaming - The Power of Supplements" and as you mention works very well with galantamine,  I will will see if Huperizine can be made to work with it too.

 

Some other things the book mentions include tiny doses of yohimbine and nicotine, although the latter is said to  damage some receptors crucial for lucid dreaming. L-Dopa from mucuna pruriens is also recommended to better quality dreams. The book is rather old , so there is no mention of using huperizine or salvinorin A.

 

Next plan of action is the alpha GPC, by itself,  with galantamine and finally with huperizine, all after 4-5 hours of sleep. But first I will take P5P for a week to investigate if this form of vitamin B6 truly helps with dream recall.

I'm interested in lucid dreams and etheric projection (astral projection on this plane). I've never had the latter, not even sure if it is a real thing or a type if lucid dream.

 

 

 

 

 

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Edited April 3 by Alchemist