∂an Posted April 12, 2011 (edited) A well researched article in New Scientist regarding fMRI measurements made during psilocybin trips, although they went for a seemingly "negative" headline where it could have just as easily been "Psychedelic drug increases the expression of genes and signalling proteins associated with nerve growth and connectivity". Psychedelic drug cuts brain blood flow and connections The mention of psilocybin as a possible treatment for depression is especially interesting. Edited April 12, 2011 by kalika Share this post Link to post Share on other sites
tripsis Posted April 12, 2011 The link needs to be fixed. It has "http://www." twice. Very interesting article. The ending is especially interesting. Wish they had expanded on the potential for resultant long-term neuroplasticity. Share this post Link to post Share on other sites
Zen Peddler Posted April 12, 2011 I once read an article that described increased blood flow and connectivity in positive experiences and the opposite in negative experiences. Share this post Link to post Share on other sites
∂an Posted April 12, 2011 The link needs to be fixed. It has "http://www." twice. Very interesting article. The ending is especially interesting. Wish they had expanded on the potential for resultant long-term neuroplasticity. Thanks, link fixed. Yeah Franz Vollenweider's work is fascinating. Share this post Link to post Share on other sites
Thelema Posted April 12, 2011 get_file.pdfHere's a recent paper from Vollenweider called "The neurobiology of psychedelic drugs: implications for the treatment of mood disorders" Fascinating! get_file.pdf get_file.pdf Share this post Link to post Share on other sites
alkatrope Posted April 13, 2011 Interesting article indeed.. I actually know a guy who takes a sub-active (no pun intended) dose of psilos every morning because he believes them to be a natural antidepressant.. Share this post Link to post Share on other sites
∂an Posted April 14, 2011 Interesting article indeed.. I actually know a guy who takes a sub-active (no pun intended) dose of psilos every morning because he believes them to be a natural antidepressant.. yeah I've heard stories of people taking small doses as a dietary supplement. It would be very interesting to monitor how ones neurochemistry and brain activity changes as a result of daily psilocybin doses. IME larger doses with a good few weeks in between is also an effective anti-depressent, the post-trip glow lasts at least a week. Share this post Link to post Share on other sites
Gunter Posted April 14, 2011 once upon a time someone i am very close to used to take very small doses of psilos at night, as a mood regulator, they were said to not be active in any overt manner. Share this post Link to post Share on other sites
tripsis Posted April 14, 2011 Small doses are purportedly effective in treating migraines and cluster headaches too. Share this post Link to post Share on other sites