teonanacatl Posted December 21, 2004 just wondering wat peoples experiences were with the bark. also wat bit of the bark is used, eg inner bark, and how much is needed??? really curious to try this :D Share this post Link to post Share on other sites
Thelema Posted December 21, 2004 as far as i know a 'standard dose', or even an incredibly "active" dose has not yet been found. the only way we can know this is from PNG researchers. or research it ourselves carefully! I used perhaps 3cmx3cmx0.5cm bark for my first sample, the first thin layer of bark was scraped off, as it had lichen material on it. My feeling is that at least 3 times this amount will start to yield dramatic results. Share this post Link to post Share on other sites
teonanacatl Posted December 21, 2004 ive been reading about Himbacine which they extracted from the bark and it exhibited strong, selective binding to muscarinic receptors of the M2 subtype. same ones that amanita muscaria binds with???? see link here http://rsc.anu.edu.au/AnnualReport/Current...t/sherburn.html Share this post Link to post Share on other sites
Fractalhead Posted December 25, 2004 I'm hoping to conduct a HPLC based isolation of himbacine (and co.) in the next 12 months or so for some serious bioassays. Retails for some ridiculous price from Sigma. Share this post Link to post Share on other sites
Floyd Posted December 26, 2004 are there any seed collection floating around? Share this post Link to post Share on other sites
Rev Posted December 27, 2004 none viable. might be come april/may if somebody knows where living plants are Share this post Link to post Share on other sites
Agamemnon Posted December 27, 2004 You know this is a really important issue. This is an extremely important tree that needs to be scientifically explored in all its facets. The fact that it occurs naturally in Australia although rarely, means its continued existence must be firmly guarded and promoted. Are there any government bodies that can be enlisted for this purpose?(or does the christian right strangle even this form of enquiry??) :confused: Share this post Link to post Share on other sites
Rev Posted December 27, 2004 Under current circumstances i would argue that the best protection given would be seed collection by committed individuals and sharing of propagation successes and failures internally alongside release of plants within our community to those who can continue this research but also these plants should be incorporated into local revegetation schemes in their natural range at the grass roots level far below the radar of govt officials pretty much the same as all our native plants like Phlebos and pituri plant first publicise later Their in the magnolia family. There has to be a massive body of specialist knowledge out there on modes of propagating this family by many means [ 26. December 2004, 20:29: Message edited by: reville ] Share this post Link to post Share on other sites