Zen Peddler Posted May 8, 2014 Any ideas why pseudoephedrine would increase someone's tolerance to caffeine rather than the opposite? Central dopamine release? Share this post Link to post Share on other sites
machineelf Posted May 8, 2014 Whether or not it is because they both release the same neurotransmitters, what comes to my mind is that you would be acclimatised to a stronger buzz with the pseudo and then having caffeine would seem weak. Share this post Link to post Share on other sites
briliant_botanist Posted May 8, 2014 machineelf Get's the box of Cuban Cigar's for the above answer imho! well done! 1 Share this post Link to post Share on other sites
-RC- Posted May 8, 2014 I would wager it has something to do with the adrenal response... 1 Share this post Link to post Share on other sites
machineelf Posted May 8, 2014 Thanks brilliant_botanist. I must say Responsible choice sounds like he knows his shit, I had to look up "adrenal response" and to me it actually seems to be pretty much what I was saying but in a more technical/ refined manner. I read (some of) the Wikipedia page 'Sympathetic nervous system'. 1 Share this post Link to post Share on other sites
-RC- Posted May 8, 2014 It's all smoke and mirrors mate... but mainly smoke 1 Share this post Link to post Share on other sites
