Galphimia glauca - strong depressant activity on the nervous system
http://0-www.thieme-connect.com.library.ne...5/s-2007-981539
"...important anxiolytic effectiveness, very similar to that produced with lorazepam...his compound exhibited an innovative action mechanism and selectively inhibited dopaminergic neurons discharges in the ventral tegmental area [16] without exhibiting interaction with the GABAergic system [17]." Planta Med 2007; 73: 713-717
Cistus creticus - sedative effects
Mat
"Pharmacological Investigation of Observed Anxiolytic Effects of the Marine Natural Product Aaptamine" Planta Medica 2008; 74
Aaptamine was administered in three doses (5, 10, 15 mg/kg i.m.) and the mice were observed for anxiolytic effects in an established chick social separation-stress model [3]. Results showed that separation-induced distress vocalizations were significantly attenuated in isolated chicks receiving 10 or 15 mg/kg aaptamine (ns = 12; ps < 0.05). However, higher concentrati
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T8D-475TD0C-5D&_user=10&_coverDate=07%2F08%2F1994&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=2c3bb6eda93339ced20cb5115469e44a&searchtype=a
Plants used for stress-related ailments in traditional Zulu, Xhosa and Sotho medicine. Part 1: Plants used for headaches Journal of Ethnopharmacology
Ethnobotanical inventory of medicinal plants used by the Guaymi Indians in Western Panama. Part I Journal of Ethnopharmacology
Volume 20, Issue 2, July 1987, Pages 145-171
http://0-www.sciencedirect.com.library.newcastle.edu.au/science?_ob=ArticleURL&_udi=B6T8D-475B9CJ-4J&_user=915767&_coverDate=07%2F31%2F1987&_rdoc=5&_fmt=high&_orig=browse&_origin=browse&_zone=rslt_list_item&_srch=doc-info%28%23toc%235084%231987%23999799997%23357126%23FLP%23display%23Volum
Note: I don't agree AT ALL with the aims of some organisations linked to below. But their effectiveness (or lack thereof) is worth studying.
Fundamentals For Effective Lobbying
Effective Lobbying Strategies
Tried out my latest successful Kanna type thing. Equal portions of Sceletium tortuosum (mostly stemmy material), D cooperi (probably) and Aptenia cordifolia (leaves, stems and roots) were fermented in plastic bag in a warm place for about 7 days. After drying in the sun for some time, the process was finished by a quick roast in the oven at 150 C to ensure dryness & to get rid of any remaining oxalates.
Inhaled a lot of the dust that came off when powdering/crushing. Ate a bit of stem (ple
Is there an ethical problem with our community relying on animal studies?
Much , if not all, of the data I've dredged up lately has been based on animal testing, not all of it pleasant for the animals concerned. I'm generally against animal testing where it involves causing profound suffering and pain (note, not all animal testing does this) Furthermore animal testing can't really capture the subjective experience of a particular drug as we can't ask the mouse: "What was it like?" I'll leave t
These links won't work for most people, sorry. Will post more info soon.
Alkaloids from Boophone disticha with affinity for the serotonin transporter
https://0-www.thieme-connect.com.library.newcastle.edu.au/ejournals/abstract/plantamedica/doi/10.1055/s-0028-1084063
A preliminary inventory of plants used for psychoactive purposes in southern African healing traditions
http://www.informaworld.com/smpp/content~db=all~content=a921267239
Review on plants with CNS-effects used in traditional S
I was thinking about the ions that migrate towards electrodes in solution. Two thoughts occur to me:
1. Will wiring a plant up with the anode on the aerial parts and the cathode in the soil cause an increased amount of negative ions to migrate out of the soil and into (and up) the plant? (Or the other way around if I have this arse-backwards, I haven't done any physics/electronics for years). If this is the case, then the direction of the current would be an important factor and should produce
http://www.shaman-australis.com/forum/index.php?showtopic=3542&view=findpost&p=31225
http://www.shaman-australis.com/forum/index.php?showtopic=22932&view=findpost&p=237276
http://www.shaman-australis.com/forum/index.php?showtopic=19199&view=findpost&p=191169
http://www.shaman-australis.com/forum/index.php?showtopic=4902&view=findpost&p=44532
More to come
Finally something kind of definitive on Candicine: "Nicotine-like action on the nervous system. In animals it provokes hypertension, while large doses have a curare-like action." Phytochemical Dictionary
USe caution when consuming large amounts of T. spachianius.
N, N, N-trimethyltyramine chloride - Starting to make sense now.