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Drug Use Linked with Brain Differences in Teens

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http://www.bluelight.org/vb/threads/726166-Drug-Use-Linked-with-Brain-Differences-in-Teens

By Rachael Rettner, Senior Writer | June 13, 2014 03:59pm ET

Teens who have used drugs even just once in their lives have brain characteristics that are different from those who have never used drugs, a new study finds.

In the study, the researchers scanned the brains of 71 Mexican-American 16-year-olds, and asked the teens whether they had ever used drugs, including cigarettes, alcohol, marijuana and other drugs. The researchers looked at whether the brain activity of certain regions was in sync (a measure known as "functional connectivity"), which suggests that the regions are talking to one another.

Among teens who'd ever used drugs, a brain region known as the nucleus accumbens — which is thought to play a role in the rewarding feeling that can come with taking drugs — was more in sync with areas of the brain in the prefrontal cortex, compared to in teens who'd never used drugs. The prefrontal cortex is involved in decision making, planning and other behaviors that require complex thinking.

But the nucleus accumbens was less in sync with an area near the hippocampus, which is important for memory formation, in teens who had used drugs, compared with those who had never used. [10 Facts Every Parent Should Know about Their Teen's Brain]

Because the study was conducted at just one point in time, the researchers cannot determine the reason for these brain differences, said study researcher David G. Weissman, a graduate student at the University of California, Davis Center for Mind and Brain. It could be that drug exposure is responsible for the differences. But Weissman said he suspects that these brain differences existed before drug use, and underlie a tendency to take risks, which includes using drugs, he said.

Weissman said the level of drug use among the teens in the study was typical of teens that age — about half had used drugs before, and they did not use drugs very frequently.

"It's possible, but seems unlikely, that that level of use would produce significant changes [in the brain], but it's an open question," Weissman said.

The researchers plan to continue to scan the brains of these teens over time, and see if there are any changes in the results, including whether there are changes in teens who start using drugs.

The new finding "brings up an intriguing idea that there are differences that we can observe in the brain in the way that it's connected that relate to whether or not kids are using substances," said Weissman, who conducted the study with Amanda Guyer, an associate professor at UC Davis, and colleagues.

Future studies could help researchers gain a better understanding of what leads teens to use substances or participate in other risky activities, Weissman said. Such studies may help researchers understand who is at risk for developing later life problems because of early drug use, Weissman said.

The study was funded by the William T. Grant Foundation, an organization that funds research on youth. It was presented last month at the meeting of the Association for Psychological Science in San Francisco, and has not yet been published in a peer-reviewed journal.

http://www.livescience.com/46321-teen-drug-use-brain.html

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Moderator
Join Date Dec 2008 Location "Darkness cannot be dissipated with more darkness. More darkness will make darkness thicker. Only light can dissipate darkness. Violence and hatred cannot be removed with violence and hatred." - Thich Nhat Hanh Posts 6,261
Yesterday 10:00

Hard to believe that ANY drug, even taken once, would have such strong (and similar) effects on the brain, regardless of the drug.
I am waiting for more data.

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Today 11:03

71 kids?

That's not very many, is it?

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Yawn correlation doesn't = causation

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Moderator
Join Date Dec 2008 Location "Darkness cannot be dissipated with more darkness. More darkness will make darkness thicker. Only light can dissipate darkness. Violence and hatred cannot be removed with violence and hatred." - Thich Nhat Hanh Posts 6,261
Today 17:02 report.gif
quote_icon.png Originally Posted by f33lg00d viewpost-right.png
Yawn correlation doesn't = causation
True, but it does say that in the article. Even the correlation is pretty interesting.
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Today 21:40 report.gif
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Originally Posted by
Engage
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71 kids?


That's not very many, is it?
And they were all Mexican American; perhaps their brains differ from other ethnic groups. Such a small population sample may provide an indication of the direction of future studies, but that's as far as it goes, and any such studies should be well designed, have a population sample capable of producing statistically significant results, and be peer reviewed.

 

Edited by CLICKHEREx

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