Marijuana blocks PTSD symptoms in rats

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Marijuana blocks PTSD symptoms in rats

Wed, 21 Sep, 04:20 AM

Marijuana administered in a timely fashion could block the development of post-traumatic stress disorder symptoms in rats, a new study has found.

The study, which was conducted by researchers at Haifa University's psychology department and published in the Neuropsychopharmacology journal, found that rats treated with marijuana within 24 hours of a traumatic experience successfully avoided any symptoms of PTSD.

"There is a critical 'window of time' after trauma, during which synthetic marijuana can help prevent symptoms similar to PTSD in rats," said Dr Irit Akirav, who led the study.

In the first part of the experiment, rats were exposed to extreme stress, and were found to display symptoms resembling PTSD in humans.

They were then divided into four groups, with the first given no marijuana, the second given a marijuana injection two hours after being exposed, the third after 24 hours and the fourth after 48 hours.

The researchers examined the rats a week later and found that the group that had not received marijuana, as well as the one that received the injection after 48 hours, displayed PTSD symptoms and a high level of anxiety.

Although the rats in the other two groups also displayed high levels of anxiety, the PTSD symptoms had totally disappeared.

"This shows that the marijuana administered in the proper 'window of time' does not erase the experience, but can help prevent the development of PTSD symptoms in rats," Akirav said.

"We also found that the effects of the cannabinoids were mediated by receptors in the amygdala area of the brain, known to be responsible for mediation of stress, fear and trauma," she noted.

While a decisive parallel between emotional states in humans and animals cannot always be drawn, Akirav was confident psychiatrists will take her research forward to implement it on humans.

© AFP 2011

NineMSN

[SunChaser]

Your probably preaching to the converted brother. I doubt most people here would deny cannabinoids in controlled doses would make a very effect sedative for someone in a traumatic situation.

But then again, maybe that's why cannabis causes people who smoke large amounts of it from a young age to develop a social anxiety disorder. From just toking up every time your a little stressed, which then causes your brain to bypass the process of dealing with the situation, which then accumulates over the years to the point where a simple personality trait (like being shy around strangers, for example) turns into a full blown disorder.

Ain't trying to rev anyone up and I've in no way lost my belief in cannabis being the most effective medical plant known to man, or my belief that cannabis is hands down the most benign recreational drug in existence. 

But if you want proof of what abusing this plant to the extreme can do, then just rock down to nimbin and check out the endless amount of hippies who are smoking grams of honey oil everyday and can't even leave the house without falling apart.

Peace