Fenris

Discovered something interesting yesterday regarding alcohol, this is specifically relevant to people with type 1 diabetes but I'm sure goes some way to contributing to a hangover. From https://biology.stackexchange.com/questions/22039/nadh-inhibits-gluconeogenesis Alcohol inhibits gluconeogenesis because 'NADH produced from ethanol catabolism leads to product inhibition'. This is the effect of metabolizing ethanol and also the reason why excess amount of ethanol can lead to hypoglycemia. Ethanol is oxidized by the alcohol dehydrogenase to acete aldehyde. This reaction needs consumes one molecule of NAD+ per molecule ethanol oxidized: Ethanol + NAD+ <=> Acetaldehyde + NADH + H+ Acetaldehyde is oxidized by the acetaldehyde dehydrogenase in a second reaction in the mitochondria to Acetyl-CoA, which produces another molecule of NADH: Acetaldehyde + NAD+ # CoA <=> Acetyl-CoA + NADH + H+ If you now take a look on the Gluconeogenesis, there is one critical step which need NAD+: The oxidation of lactate to pyruvate by the lactate dehydogenase which then cannot be processed into oxalacetate, phosphorenolpyruvate and so on. Adding excess NADH shifts the reaction equilibrium completely to the side of lactate and also leads to the producion of additional lactate, leading to hyperglycemia and lactic acidosis. Acess NADH from the ethanol oxidation inhibits the oxidation of fatty acids in the liver - this process also generates NADH for the production of ATP. NADH signals this process that enough energy is available in the cell. And finally excess NADH also inhibits the malate dehydrogenase reducing the amount of oxalacetate for gluconeogenesis further.

Many thumbs up. A steel hull with a supercharged v8, the ocean going drug runners transport of choice, nice work.

What is the hull made of? I have heard that steel hull yachts are good as an offensive weapon and resist gunshot fairly well, & would be an easy repair from a gunshot wound. I actually heard a story of a yacht convoy that got hit by pirates and they used the steel hull to charge the pirates, it left the pirates boat in 2 pieces sinking in the ocean. This was after the coastguard declined to get involved. If I didn't have a young family to take care of I would be totally down for some more ocean adventures.

What an incredible adventure. Watch out for pirates, seriously, and pack plenty of thermals & something to barter.

I couldn't comment on chacruna specifically but the spirit of Aya showed herself to me when I was in Peru as the character of Pilar from For Whom The Bell Tolls. From http://www.sparknotes.com/lit/belltolls/canalysis.html Pilar Arguably the most colorful and likable character in For Whom the Bell Tolls, Pilar embodies the earthiness, strength, and wisdom of the Spanish peasantry. A large, robust, part-gypsy woman, Pilar exercises great influence over the band of guerrilleros—in fact, we quickly become aware that Pablo leads the band in name only. The strong and stable Pilar provides the motivating force behind many of the novel’s events. She pushes Robert Jordan and Maria’s romance, commands the allegiance of the guerrilla fighters, and organizes the guerrilleros’ brief alliance with El Sordo. She acts as the support structure for the camp as she unites the band of guerrilla fighters into a family, cooks for all, and sews Robert Jordan’s packs. In short, Pilar manipulates the most important characters in For Whom the Bell Tolls and sets in place many of the encounters that drive the plot. Pilar, though practical, often relies on intuitive, mystical, gypsy folk wisdom. Shrewd and worldly-wise, she claims a deep connection to the primitive forces of fate. She claims to be able to smell death, and she describes the smell in repulsively naturalistic detail. She reads palms and interprets sexual experiences. Despite Robert Jordan’s cynicism, Pilar’s predictions do come true. Pilar exhibits the inevitable sadness that comes with knowledge: “Neither bull force nor bull courage lasted, she knew now, and what did last? I last. . . . But for what?” In the end, the only aspect of Pilar’s personality that seems not to show wisdom is her unswerving commitment to and belief in the Republican side, which ultimately loses the war.

I was in Darlington hills (WA) last weekend taking a walk with the family & found some almost invisible, well camouflaged mushrooms growing out of the red pea gravel dirt . with the compaction Im surprised they were able to grow out of the path. Don't know what they are, but pretty cool none the less.

I was under the impression that Erythrina sp were deliriants, similar possibly to brugs, but not solinaceous. A quick check on here https://www.erowid.org/herbs/erythrina/erythrina.shtm does mention deliriant. Careful with that bioassay.

Some South West sub finds ;-)

I experimented with OT years ago but was unable to discern anything. Maybe if I was in a room full of people I may have felt more connected and trusting, but trying it by myself I got nothing.

By far the best thing I have taken for memory is lecithin. Its a precursor to acetylcholine and the first couple of weeks it was giving me such a buzz I couldn't take any at dinner time. My recall and cognitive abilities came back quickly and I didn't have to struggle to remember words. I'm not sure why things were taking a turn for the worse but lecithin got me back to feeling sharp again.

Great stuff

I have had psoriasis for 30 yea years and am better now than at any time in the past. I believe after extensive trial and error that psoriasis is highly correlated with digestive health. I have had positive results from colostrum and excellent result from psyllium husks. Since getting on the UltraClean 85 liquid fish oil a lot of skin complaints have been healing up and taking mastic gum was of surprising benefit. I have a hunch that the mastic changes the gut flora for the better and psyllium helps to eliminate waste better. I also think there is something to do with not processing fats very well. Apparently a statistically significant number of people with psoriasis end up with non alcoholic fatty liver. I have been taking lecithin as well for its cognitive enhancements but it is an emulsifier and helps to protect the liver. Anyway psyllium,liquid fish oil and mastic gum have cleared up my psoriasis and dermatitis by about 95%.

Awe man now I have the hankering for that round the world on a yacht thing again. Unfortunately as well as being a bit of a yachtie I get terribly seasick. I think center console is a must, and for some good ocean sailing I personally would prefer 36ft and up, I reckon 40ft is a sweet spot. I must say the 2 masters, sloops & ketches are things of beauty. Interesting thing is that being on the ocean on a yacht for a while can do funny things to you, I could have sworn I was hearing quiet conversations in the rigging for a few nights on the Med, I put it down to the spirits of past sailors, it was a little eirie at 3am.

The yacht was a charter and the guys who hired it panicked and thought it was going to sink, there was some water getting in through the front hatch (it was pretty rough), they got air lifted by a British naval vessel about 36 hours prior to us finding it. The insurance company was involved, basically it was now theirs and they paid us to bring it back from Algeria. I'm not sure it is possible to wholly claim salvage when the insurance company wants it back.

I sailed the Med on a yacht delivery, from Gibraltar to Cyprus. Three days out of Gib we came across an abandoned Beneteaux Oceanus 43 footer in a storm. There was only 2 of us so we got a yacht each, me on the salvage. We went to the nearest port in Algeria and were put under port arrest as they thought we had stolen the yacht and killed the crew, we had a couple of very friendly armed guards for about a week before the whole mess got sorted out. With one yacht each we sailed 25 hours to Majorca and left the salvage with an insurance assessor before continuing on our way to Larnaca in Cyprus. That is the very short version with lots left out and hardly does the story justice. It was hard work and an awesome adventure. I got a cut of the salvage worth around $8k which got me some more traveling. I spent a month on the boat all up. Just one of my "adventures of a lifetime" :-) I started out racing mirror dinghies when I was in high school. If I didn't have a young family to support I'd be up for more salty adventures for sure, its pretty awesome stuff.

INTJ seems to me to a Tee

Epicaricacy

From http://www.canberratimes.com.au/federal-politics/political-news/tax-toke-the-budget-office-models-gst-on-marijuana-20160129-gmhjli.html Just what are they smoking down in the Parliamentary Budget Office? The normally conservative federal institution has done some highly unusual economic modelling based on the question: how much money could the Turnbull government raise if it legalised and then applied the GST to marijuana? The answer is about $300 million a year. And that doesn't even include the increased tax toke – sorry, take – from the inevitable boom in sales of pizza and Doritos. The PBO, which was set up to provide independent and non-partisan budget analysis to politicians, did the costings at the request of libertarian crossbench senator David Leyonhjelm, who wants marijuana fully legalised. If such a policy were introduced in July 2017 it would raise $600 million in GST revenue in the first two years, the PBO found. That money would flow on to the states but the policy would also help the federal government through reduced law enforcement costs. The government would save about $100 million a year in reduced Australian Federal Police and Australian Border Force costs, the PBO says. The costing is based on some key assumptions, chiefly that all states and territories would align with the Commonwealth in fully legalising marijuana, hemp growing and the production of hemp for human consumption. It's also based on there being no restrictions on marijuana production, such as quotas or restrictive licensing. It also assumes there would be no impact on excise collections from the sale of alcohol or tobacco. "A number of studies have analysed whether marijuana is a complement to or substitute for alcohol and tobacco. However, the literature has not reached a consensus, with the findings of different studies in conflict," the PBO says. The impact of the proposal was calculated by applying a 10 per cent GST rate to current estimates of household consumption expenditure on marijuana. However the PBO predicts the proposal would result in an increase in marijuana supply and demand, from 333 tonnes in 2016-17 to 395 tonnes in 2018-19. The PBO stressed these costings should be considered "low reliability". "There is uncertainty regarding the price and quantity of marijuana currently consumed and the price and quantity of marijuana that would be consumed in a newly legalised market," the PBO writes. "It is also difficult to separately identify marijuana law enforcement activities as these are often integrated within broader law enforcement activities." Senator Leyonhjelm said he does not recommend the use of marijuana except for medical purposes but recreational use should be for adults to decide for themselves. "Prohibition has achieved absolutely nothing except tie up police resources and provide revenue for criminal gangs," he said. And to polish that off check out here http://www.macrobusiness.com.au/2016/02/time-to-legalise-pot-to-pack-budget-cone/

I cant imagine it getting any better from her on in. By the end of 2017 we will probably be in shtf territory. We are only about 1/4 to 1/3 the way through the mining investment bust, there are still 10 of thousands of jobs to loose in that sector, then there is the closure of the car industry in 2017 to compound it all, the USD will possibly be at 45c to the AUD by then. I can only see prices stagnating or going down over the next 5 years. I hope you aren't into negative equity. All the best.

I'm heading down to Collie next week for a delivery/pickup for work & should be able to swing past the spot where one of the forum members got some red milo recently.

Years ago I could get red Milo or millet or sorghum (not sure if they are all the same stuff) and it was a good grain for growing certain things on when wheat wasn't preferred. I currently can't find anywhere that sells it, City farmers was my first try in the birdseed section but no luck. Does anyone have any idea where I could get some red Milo in Perth?

Check out what happened to the Cypriots a couple of years ago with bank bail ins, the legislation was enacted here a few years prior which enables the banks to take your deposits in the event of a collapse. Cash outside the banking system isnt a terrible idea. I like gold & silver coins for long term in case of shtf scenario. Beta shares ETF USD let's you buy USD on the stock exchange, made 20% in the last 15 months on that one. I like good quality gold producers in AUD as a play against catastrophe. The ASX is collapsing and the gold miners are mostly doing fine.

I found this on anthocyanin rich fruit: Comparison of the total phenolic content, total anthocyanin content and antioxidant activity of polyphenol-rich fruits grown in Chile http://www.scielo.cl/pdf/ciagr/v41n1/art05.pdf The maqui fruit appear to be this https://en.wikipedia.org/wiki/Aristotelia_chilensis And looks to be brimming with anthocyanin

I picked up 5kg of rye grain from Brew Mart Brewing supplies in Bayswater for $25, the proprietor now is well versed in truffles :-). You need to request the larger size as it was only packaged in 1kg bags. His query as to why I needed 5kg led to the sclerota conversation. The rye looks good too. Back in my big pharma days I had access to industrial autoclaves, I should have sterilised some 200L barrel full's when I had the chance

I might try rye grain, its easy to get at the brew shop and a quick search indicates "rye berries" which I assume is rye grain apparently works very well in sclerota formers.