The use of anticholinergic (specifically, antimuscarinic) drugs is already well established in mainstream medicine for the symptomatic treatment of hyperhidrosis (excessive sweating) and it is indeed fairly effective. Unfortunately these types of drugs, especially those that readily cross the blood-brain barrier can produce a whole bunch of unpleasant side effects when administered orally. The medical community understands this and a topical product has been developed specifically for this ailment in the form of a glycopyrronium-bromide laced disposable wipe.
While my plants may love summer, I and many others find it hard to embrace it when constantly drenched in sweat. Personally, the heat itself doesn’t actually bother me, it’s just the perpetual drowned-rat look and feel that I detest. While not officially suffering from hyperhidrosis, as it is not a year round thing personally, my medication does lower the temperature threshold for me so for 3-6 months a year, I may as well have it. Anyway, enough 1st world white boyin’ from me...
Recently I bought a Brugmansia to add to my ethno garden once again and today was pondering the possibility of preparing and using it topically for sweating. Maybe I can love summer after all haha... anyway, seeing as the tropane alkaloids within are antimuscarinic anticholinergics too, they should indeed work just as effectively as the pharmaceuticals used. I even found an Ayurvedic website that lists it as a therapeutic use for Datura so this is far from an original thought of mine.
Just thought I’d share the idea as an interesting topical use of tropane-bearing plants. Would also love to hear if anyone has tried using such plants for such purpose, how one may go about preparing them for topical use safely (and without ending up with a flying ointment instead ) or anything else anyone would like to add!
Peace!