kenny Posted June 7, 2009 I found this thread at the shroomery... Can THC Help Some Schizophrenics? June 5, 2009 - mpp.org Report cites "grossly psychotic, assaultive," schizophrenic "became calm, logical, nonviolent and cooperative within days" after taking THC The surprising finding that THC might help at least a small percentage of schizophrenia patients for whom conventional treatments have failed was reported in the June issue of the Journal of Clinical Psychopharmacology. This is surprising because, as the British government’s Advisory Council on the Misuse of Drugs reported last year, "there is clear evidence that the use of cannabis may worsen the symptoms of schizophrenia and lead to relapse." The ACMD -- a far more objective body than any U.S. government outfit remotely connected to drug policy -- did not consider marijuana to be a significant cause of psychosis in otherwise healthy people; its report reflects a broad consensus that marijuana (and specifically THC) can worsen the prognosis of schizophrenics or those with a genetic vulnerability to schizophrenia. But doctors at the Rockland Psychiatric Center in Orangeburg, N.Y., reviewing the records of one severely ill patient -- a man who was "grossly psychotic, assaultive, disorganized" and not responding to conventional treatment -- noticed that he had a history of "calm behavior when he was using marijuana." So as an experiment, they prescribed THC capsules (dronabinol, brand name Marinol). "Remarkably," they write, "he became calm, logical, nonviolent, and cooperative within days and was discharged within weeks." They then tried the same thing with five other patients with a similar history -- unresponsive to conventional treatments but showing some signs of improvement when they smoked marijuana. Three of these "improved to a clinically significant extent," one showed no significant change, and one got somewhat worse. That’s a remarkable level of success in chronically ill patients for whom conventional anti-psychotic drugs had failed, "in which success with any intervention might be unlikely." The article goes on to lay out some possible explanations, but at this point no one knows for sure why this small group of psychotic patients had an anomalous and positive reaction to THC. What is clear is that the relationship of cannabinoids to schizophrenia is more complex and variable than even many experts -- much less anti-marijuana propagandists – have acknowledged. http://journals.lww.com/psychopharmacology...nabinol.10.aspx Share this post Link to post Share on other sites
faustus Posted June 7, 2009 hah, i made this call on the forums years ago but was shot down. in some genetic knockout mice models of schizophrenia cannabis has antipsychotic properties. similar links with tobacco smoking have also been demonstrated. Share this post Link to post Share on other sites
woof woof woof Posted June 17, 2009 i think that anything that gives somone something to hold on can help create stability in their lives. for allot of people it's a bible or or a koran or other religious text. so it does not supprise me. it's all about conditioning. If certain cellular/signalling mechanisims (chem pathways/cascades) in the brain are not funktioning properly then that will also determine the effectiveness of ANY medication. as with any mental disease,...... stability is created through Meds, rest calmness & relaxtion. Those then become the conditioning patterns to establish a new foundation or to get in touch again with the old foundation so that one can pick himself up again. (depending on the type or gravity of the mental illness of course!) cannabis CAN help people to relax,.... tabacco can also help to calm nerves...... so that are also big contributing factors. My personal experience is that cannabis gets me hyper energy overdrive............. soooooo I am 100% sure it can and probably will have adverse effects in most people with mental illness. the brain is a delicate organ. so you should treat it that way too! Listen to it! 5milion years since the split from the other great apes is allot of f'nn time. What I wonder about is............ what role has mental illness played in our evolution. My guess is that it could have contributed to thinking OUTSIDE THE BOX.... gaining interesting insights on life perhaps???? Share this post Link to post Share on other sites
MindExpansion Posted June 18, 2009 Hmm I think I've read of antipsychotic properties of some of the other cannabanoids, cannabidiol was the one in particular i think... Peace Share this post Link to post Share on other sites
mutant Posted July 21, 2010 What I wonder about is............ what role has mental illness played in our evolution. hehehe, been wondering about this for years maybe psychedelia / inebriation / psychosis were not so distinct from oneother 100.000 years ago Share this post Link to post Share on other sites
