Cactouasca ?

[simon_marklar]

http://www.azarius.nl/news.php?newsindex=89

Pachycereus pringlei + MAOI

Sasha outlined the four basic types of one-compound psychedelics and then described ayahuasca which is a two-compound psychedelic--1) a DMT analogue plus 2) an MAO inhibitor to prevent the first from being destroyed. There are many varieties of ayahuasca that differ in the plant substances that provide these two components--that is, many different plants that carry DMT and many plants that carry MAO inhibitors. There is even something called "pharmauasca" which is not derived from plants at all but which is simply synthetic DMT (in a capsule) and synthetic MAO-inhibitor in another capsule.

Earl's cactus was different from all of these--it contained a lot of MAO inhibitor but no DMT. (DMT, says, Shulgin is found everywhere in nature but never in cactuses). Instead in Earl's cactuses there were mescaline-like substances that have no psychoactive effects on humans--by themselves. Shulgin's guess is that the presence of the MAO-inhibitor in the cactus protects the mescaline-like molecule from degredation and hence permits it to act on the brain in a mescalin-like way. So Earl's cactus is indeed a "brand new elixir"--a heretofore unexplored two-compound psychedelic for which Shulgin coined the term "cactouasca". CACTOUASCA--You heard it here first.

[Ymir]

great another word that i can't pronounce correctly. damn you linguistics! damn you to hell!

[Rev]

nice try but this word is already in usage for a harmala / mescaline mix

ie cactus brew with harmala or capi leaf or vine

peopel have been doing it for years, there is speculation if not proof that its also traditional in zones where capi and cactus overlap

if its a diff mode of action then theyll have to be more imagiunative in the names

[Gunter]

I wonder why Shulgin didn't mention that in aya the betacarbolines have two functions. One is as an SSRI that has the effects of potentiation (THbC), the other is the MAOI which he mentioned (harmine/harmaline).

Caapi contains the SSRI's in greater concentrations and you may find that caapi brews often require less DMT than Peganum brews.

I wonder then though if the THbC content of caapi can potentiate mescaline? Making a caapi mesc brew require less cacti than a Peganum.

DMT was known and thought to be inactive, so some of the PEA's in cacti are active with MAOI? Sounds like there is work to be done.