Jump to content
The Corroboree

Carpobrotus edulis - any modern bioassays?


Alchemica

Recommended Posts

I totally neglected looking into Carpobrotus sp. at all but wondering if they have been explored more recently by anyone?

Carpobrotus edulis has long been used as food and in traditional medicine in South Africa. This plant is used by the traditional healers to treat tuberculosis, diabetes mellitus, sores, high blood pressure, intestinal worms and constipation. 

 

image.thumb.jpeg.e7296a9be3c0733fe508cebf39ef58ec.jpeg

"...contemporary bioassays of this species in the US have [in some instances] revealed it to sometimes be more potent than Sceletium tortuosum, though of similar quality (pers. comms). C. rossii which is much more common than C. edulis in Australia ... appears to be inactive"  - Garden of Eden, S. Voogelbreinder

Leaves from C. edulis have a nutritional profile suitable for human consumption. 

- in vitro biological activities were described for C. edulis including antioxidant, immune modulating, antimicrobial; anticholinesterase and anti-tumoral activity
- antidiabetic, anti-inflammatory and antioxidant properties validated
-  Exerts a high in vitro anti-neuroinflammatory activity and contains compounds with the potential to prevent neuronal cell damage 
 
Primary literature interest in the medicinal effects has been through the phenolic fraction, of which is particularly abundant.

 

image.thumb.png.d6f7fb53c98dbb22bfdb8c43cc59cf1b.png

 Some phytochemical analyses have noted: β-amyrin, oleanolic acid, uvaol, monogalactosyldiacylglycerol, catechin, epicatechin and procyanidin B5

image.thumb.png.99f62457c59a503d0acf478acdd7e0a5.png

 

Máximo P, Ferreira LM, Branco PS, Lourenço A. Invasive Plants: Turning Enemies into Value. Molecules. 2020 Aug 1;25(15):3529. doi: 10.3390/molecules25153529. 

M.I. Rocha, M.J. Rodrigues, C. Pereira, H. Pereira, M.M. da Silva, N. da Rosa Neng, J.M.F. Nogueira, J. Varela, L. Barreira, L. Custódio, Biochemical profile and in vitro neuroprotective properties of Carpobrotus edulis L., a medicinal and edible halophyte native to the coast of South Africa, South African Journal of Botany, Volume 111,2017,Pg 222-231 doi:10.1016/j.sajb.2017.03.036

R.B. Mulaudzi, A.O. Aremu, K.R.R. Rengasamy, S.A. Adebayo, L.J. McGaw, S.O. Amoo, J. Van Staden, C.P. Du Plooy, Antidiabetic, anti-inflammatory, anticholinesterase and cytotoxicity determination of two Carpobrotus species, South African Journal of Botany,Volume 125, 2019, Pages 142-148 doi: 10.1016/j.sajb.2019.07.007.

Omoruyi, B. E., Bradley, G., & Afolayan, A. J. (2012). Antioxidant and phytochemical properties of Carpobrotus edulis (L.) bolus leaf used for the management of common infections in HIV/AIDS patients in Eastern Cape Province. BMC Complementary and Alternative Medicine, 12(1). doi:10.1186/1472-6882-12-215 

B. Ibtissem, C. Abdelly and S. Sfar, "Antioxidant and Antibacterial Properties of Mesembryanthemum crystallinum and Carpobrotus edulis Extracts," Advances in Chemical Engineering and Science, Vol. 2 No. 3, 2012, pp. 359-365. doi: 10.4236/aces.2012.23042.

  • Like 1
Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

×
×
  • Create New...