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Tyramine, 5HTP interactions. It's real, and very much NSFW
Darklight posted a topic in Chill SpaceTL:DR I always thought the tyramine/ aged cheese/ dieta thing was shaky til now, having read both sides and never experienced any issues prior since forever. Now I'm a believer Posting here so I don't spam the shit out of my mates. It's still happening, albeit at a lower level, and I'm super relaxed and everything seems like a good idea. After this I'll step away from all the keyboards before I start posting love letters on 4chan or something else godawful Been slaving over a hot spreadsheet for over a week ( queue tiny violins ). While I'm completely absorbed in computer stuff, my go to food is cheaparse Aldi Stilton, leafy greens and whatever fruit's in the garden. For days. In this case a week. A tiny stinky block of Aldi Stilton can last for days and there''s no washing up and it's brain food for spreadsheets Pressed Send on the spreadsheet. Wandered about feeling residually wired for a coupla hours and it was pissing me off, because Job Done, validated, tick, right? Had some 5HTP. Didn't measure it. Prolly a bit more than I should have, and would normally have- but not *that* much more. But when I've done that in the past all that happens is I get a bit anxious then it wears off and I'm all relaxed like it says on the box At +1 hour in things get weird. I think it was an hour, but it was getting weird so we'll call it +1 hour. I can't remember what the initial symptoms were because I'm not back yet. Mostly classic hiatus hernia I think, I looked it up. Old people thing. Burping, dizziness, feeling of fullness. Yeah, so I put it down to that. I'm old, bits of me recovering from whatever the fuck I had last year. That. 5HTPs never been an issue ever before At +1.5 hours I'm lying down wondering if someone has messed with my 5HTP container. And even I am not that stupid. And all my guests are awesome. It's looking incredibly serotonergic in here, but it's not your classic serotonergic. Temperature is constant. No change in heart rate. There are waves of...serotoninishness tho. Flickery visual disturbances are making me want to close my eyes. Scrolling Facebook on the laptop is even more of a physical nightmare than usual because visual disturbances. Is less worse if I stop scrolling down webpages or switching between tabs. But the effect isn't quite...drukgs. It's just not that sparkly for the level of physical discomfort either. The only thing I can think of is 5HTP. Must be a novel reaction now I'm old Ride it out. Feel like total shit, dog is getting worried etc. Doesn't feel life threatening, so no hospital. Mostly cos I do not want to go to hospital and tell them I took something that wasn't drugs but feel like it's a serotonergic response to 5HTP. That shit never ends well. And not quiiiite bad enough for the ambos yet. But no fun and getting slowly worse At +2 hrs approx it dawns on me that activated charcoal might help. Sop it up maybe. Swill a spoonful down in H2O and feel better At 2.5 hours I don't feel better enough, so I mung another spoonful in water and lay back down At +3 hours I had to stand up suddenly. I will never get the Stilton out of the curtains and the bathroom looks like it's been vandalised by a psychopathic goth teenager. Wall to wall charcoal But once I recognised the Stilton it all made sense- tyramine. Fuck I've heard of the MAOI response, but this is ridiculous. It was 4 hrs since my last Stilton hit before I took the 5HTP. What am I, made of fucking glass or something? Needed a couple more AC solutions between then and now, but the worst of it is gone The moral of the story is: Sometimes internetty things are true, for some people. And always keep human grade activated charcoal in your kitchen pantry. I don't have a kitchen pantry, but if I did that's where I'd keep it. Listen to your Elders. Not me tho, I'm still a little shaky. Often there is a reason for The Things. Like not eating the tops of Kava plants, and being careful about your food when anticipating ceremony. Those people know their shit, much respect I had to open the fridge ten minutes ago and the fucking Stilton is still in there and I was like a vampire at sunrise. This is gunna go on for a while I think. Even the smell... Feel heaps better tho.