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  1. mindperformer
    Lagochilus inebrians (intoxicating mint): The diterpene-alcohol Lagochiline was found to be an antagonist at metabotropic glutamate receptors: http://stimuluswatch...hoactive-plants this action was also observed at Lithium and nootropics the mGlu-5- receptor was shown to play a role in cocaine addiction. mGlu-Rs also play a role in the sedative action of alcohol and some ligands have analgesic action. Lactuca virosa (letuce): Inhibits NEP enkephalinase and therefore enhances the endorphine- levels which leads to analgesic and anti-opiate-withdrawal effects. (FUNKE et al 2002): http://www.wildlettucehq.com/ (halfway through on the site you can see the study on the NEP- inhibition) Additional it works as a Adenosine receptor agonist and acetylcholinesterase inhibitor (nootropic).
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