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I actually feel that the TGA's agenda towards scheduling (a step or two down the ladder just like psilocybin and MDMA) will keep going on its merry way, regardless of what our communities say, as we aren't corporate/venture capitalists/pharma giants with the cash to lean hard where they need to. Smoke and mirrors to distract and obscure themes like ecology, preservation, self sufficiency, self-care and sovereignty over consciousness, as we move inexorably closer to pay to play, synthetics and production line manufacture of anything that can be sold for a few bucks from the psychedelic realm...
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I think we're all critical of Prue rather than Liam. I know people who we're interviewed for the book and very little of what they said was applied appropriately. They claim a lot was taken out of context or altered significantly, sometimes beyond recognition. I'm sure Prue had good faith. I've met her. She strikes me as genuine and kind.
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Citizen Plant Science - Exploring the Aizoaceae
Alchemica replied to Alchemica's topic in Pharmacology, Chemistry & Medicine
I've been busy expanding on this research, hopefully it's of interest/inspiration to others: So far the research extends to: Citizen TLC Phytochemical Screening of Diverse Mesembryanthemums https://pdfhost.io/v/gugGrtnCj_ Phytochemistry of Aptenia https://pdfhost.io/v/dq6SpR9nM_aptenia Citizen TLC analysis of marketed commercial Sceletium tortuosum products: https://pdfhost.io/v/SVvI3PQwb_TLC_commercial_sceletium_produc Using TLC to guide discovery of hypothetical new Kanna substitutes https://pdfhost.io/v/A4u.08qVQ_kanna_substitutes_TLC Utilising yeasts to encourage the bioconversion of mesembrine-type alkaloids https://pdfhost.io/v/cgI1KIK~l_yeasts_to_encourage_bioconversi Hope to add maybe one more on characteristic novel Sceletium species. - Last week
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Sounds like a nice idea. I don’t have a property but if the dates work out I’ll be there.
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Hi All, been a while since my last lurk around the forums I've got some Courtii seed available for purchase. $25 per 30+ seed pack. Or $1 each. Harvested January 2022 from seed grown trees in southern Tasmania. Message for inquiry ✌
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Ceremonial Cacao Vs Cacao Nibs Vs Raw Cacao powder
Ishmael Fleishman replied to Ishmael Fleishman's topic in Chill Space
Yes heavy metal contamination is a big problem with cacao and chocolate - especially with the stuff from Peru and Ghana because of the soil. Oddly enough it is NEVER mentioned in the hype. However I think its a plant problem just like Rice has very high levels of chromium, cadmium, arsenic, and lead. Thanks for the info on Criollo and Forastero types I will have a look at finding a Criollo source for my cacao. -
Ceremonial Cacao Vs Cacao Nibs Vs Raw Cacao powder
fyzygy replied to Ishmael Fleishman's topic in Chill Space
There's probably a lot of hype around ceremonial cacao, to justify the added value. According to one purveyor: There are two major common types of cacao beans–Criollo and Forastero. Forastero beans are more common for their sweetness and resilience to destruction in industrial farming. Therefore, those beans are more commonly used in today’s cacao products. On the other hand, ceremonial cacao powder is made using only Criollo beans, which are milder and have a higher concentration of restorative properties. Many advertise a "100% pure" ceremonial product -- although it's reported by scientists that cadmium contamination is an issue, depending on which region the beans were grown in. -
I have been enjoying raw cacao and I have become interested in Cacao. Cacao is one of the mostly widely used psychoactive plants in the world. However like tobacco it has been appropriated and debased. I have given up coffee it caused to much anxiety and sleep issue and their was a definite addictive craving for coffee. The first two weeks after coffee was a sleepy daze. Raw cacao in massive 50g dosage can be stimulating however it is a far more pleasant not as jittery. My experimentation has made me interested in the nuances. Specifically I am interest in the difference between Ceremonial Cacao Vs Cacao Nibs Vs Raw Cacao powder. Their is allot of marketing in this space. So I am not sure what is actual. But as far I understand you have the cacao bean, you break it up you should have nibs. Cacao powder is made by pulverizing the cacao nibs to powder. If you keep grinding the nibs into turns into Cacao Paste or Ceremonial Cacao Paste. Is it that simple? Just like peanuts turn into peanut powder and then emulsifies into peanut butter. I see mention of "Ceremonial Cacao has not been defatted and is minimally processed under low temperatures to maximize its health benefits". I know that any mechanical grinding cooks anything through simple friction. I know that the claim of raw is questionable. However is their any real difference beyond the level of processing and marketing? I know that Dutch process cocoa is defatted and treated with alkaline chemicals. Changing the alkaloids and bitterness in the process. Changes in this process account for difference between Hershey chocolate and say Cadbury. Hershey has a very unique taste profile.
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It's getting cold in Melbourne now, Sub are poping; maybe we need an indoor meet around a fire this winter; anyone got a cool property
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TGA approves psilocybin and MDMA for treating depression, PTSD
RonnySimulacrum replied to fyzygy's topic in News & Notices
Here a much better story - Changing Minds The remarkable story of a woman taking part in Australia's first psychedelic-assisted therapy trial. For Lindy Bok, it's a profound and deeply emotional experience as the treatment helps her confront anxiety around death. https://iview.abc.net.au/video/NC2302Q013S00 -
Yes, this is a hard one, Psychedelics are no longer fringe topics, and our community is being showcased for good or for bad. We need to be ready for more of this as the TGA decision has the media working on Psychedelics stories left, right and centre. Liam has done a lot of good work for the community, and a couple of us gave an interview for the book (that this chapter was lifted from); sadly, the use of our words fell beyond our control as the media often does. We thought is was a book for plant nerds not the major media spaces, but that life, sadly. Attention is a good and bad thing; even on a bad day I think Liam has a better voice generally for the community than many out there. Liam has volunteered much of the last 10 years of his life trying to help this space, however, he is very much still learning like we all are. This situation could have been better on many front and i not just talking about Liam here, even myself, i made mistakes around this, and need to live with that. It's a balance between trying to show we are good people and we have good gardens and good wellness stories and the media diving in like vultures on our community and gardens. The chapter in question here was Liam chapter was his own story, associated with his work with us, but not a direct part of his role with EGA. At EGA we generally do not do media. We rather focus on making our own content, and self-publishing. This has again made us think hard about the next time we do or will. I support Liam and his work more generally, I feel he is an asset to the community and I know he released a statement on that matter, so I recommend reading that as part of this discussion.
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EGA Videos - Psilocybin mushrooms in Australia: From ID to Therapy
RonnySimulacrum posted a topic in Mycology
EGA has a special playlist for this Sub mushroom season - Psilocybin mushrooms in Australia: From ID to Therapy Emerging research around psilocybin-assisted psychotherapy, drug law reform, ecological sustainability, harm reduction and mycological research all intersect with the needs and values of our ethnobotanical community. Enjoy this playlist at the myceliating edge of psychedelic fungi. Featuring Dr Vince Polito, Dr Shevaugn Johnson, Dr Symon Beck, journalist Rich Haridy (TBC), mycologist Caine Barlow, Horticultural Science Alistair Mctaggart. Click the below link for all the videos Psilocybin Mushrooms in Australia: From ID to Therapy --- About EGA. Entheogenesis Australis is a charitable educational organisation established in 2004. We provide opportunities for critical thinking and knowledge sharing on ethnobotanical plants, fungi, nature, and sustainability. Through our conferences and workshops, we aim to celebrate the culture, art, politics and community around medicine plants in the hope to better wellbeing for humankind and the planet. To find out more about what we do, head over to our organisational website - www.entheogenesis.org Also, head to the conference website for more info - www.gardenstates.org Be sure to stay up to date by joining ethnobotanical our mailing list HERE - Earlier
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Better to take a small sample of mycelium from the patch or at the base of a fruit, and use it to inoculate some substrate, then spawn that to a new area.
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https://archive.org/details/practicalscience0000prat A gentle introduction to the science of gardening.
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Syriab Rue/Ayahuasca & MAOI: Are the Dangers Real
Ishmael Fleishman replied to Ishmael Fleishman's topic in Pharmacology, Chemistry & Medicine
Nexus is interesting and I try to read it at times however its focus on extractions and chemistry is not my thing. I start reading something and within a sentence I need a dictionary, Wikipedia and duckduckgo. I am more into the culture, history and the spirit of the plant. Also the site is just so visually painful to look at. -
Syriab Rue/Ayahuasca & MAOI: Are the Dangers Real
Ishmael Fleishman replied to Ishmael Fleishman's topic in Pharmacology, Chemistry & Medicine
What are people thoughts about possible interactions between Cocoa and harmala considering that Cocoa is a source of caffeine and Phenethylamine. Also it looks like cocoa is a powerful MAO-B inhibitor. However -
Syriab Rue/Ayahuasca & MAOI: Are the Dangers Real
Trip replied to Ishmael Fleishman's topic in Pharmacology, Chemistry & Medicine
Nexus might be worth checking out. -
Syriab Rue/Ayahuasca & MAOI: Are the Dangers Real
Ishmael Fleishman replied to Ishmael Fleishman's topic in Pharmacology, Chemistry & Medicine
Thank you so much for the explanation - There is surprisingly little information on effects and use of straight harmaline. -
Syriab Rue/Ayahuasca & MAOI: Are the Dangers Real
Trip replied to Ishmael Fleishman's topic in Pharmacology, Chemistry & Medicine
Both harmine and harmaline are reversible inhibitors of monoamine oxidase A (RIMAs). The mechanism of action is different to irreversible MAOIs like: Isocarboxazid, Phenelzine or Tranylcypromine. The bonds for reversible inhibitors are more easily broken as they are bonded through non-covalent mechanisms. Irreversible MAIOs permanently inhibited and altering the receptor site they target. Which is why pharmaceutical MAOIs have more dangerous interactions, whereas many who have extensive use with harmala will tell you the fears are offstated. Ofcourse mixing harmala with stimulants, certain pharmaceuticals, amphetamines etc isn't a good idea and there are ofcourse other factors such as half lives etc, but generally interactions with harmala are overstated. Now THH found in caapi is a bit different. It is thought to be a SRI with minimal reversible MAO-A activity. But i believe this is still controversial. -
Syriab Rue/Ayahuasca & MAOI: Are the Dangers Real
Ishmael Fleishman replied to Ishmael Fleishman's topic in Pharmacology, Chemistry & Medicine
So it looks like harmala is a MAO-A inhibitor. I am not a chemist so my grasp on these things is crude. Harmala is an MAO-A is a monoamine oxidase enzyme Inhibitor only. Not a MAO-B. Beyond this I do not understand much. So the Dr. claims are semi -true in part because modern pharmaceutical MAOI's are more targeted not only because less Tyramine in our foods. I started to dig on drug interactions and this the list I came up with: Beta-blockers > I have taken them in the past to reduce he ephedra > cold & flu tablets > diet pills > Ephedrine stimulants > I do not like stimulants and have even cut out tea and coffee amphetamines > this includes the Mescaline (3,4,5-trimethoxyphenethylamine) & San Pedro pharmaceutical MAOIs rasagiline for Parkinson disease; Amifampridine for muscle disease Anticholinergic drugs Corticosteroids > this would be a concern because GP's inject like they are handing out candy > GP suggested an injection to me today. SSRIs Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) Triptans > migraine or cluster headaches Tricyclic Antidepressants BuSpar (buspirone) Eskalith (lithium) Desyrel (trazodone) Analgesics like Codeine, Fentanyl, Tramadol > I was in hospital two months ago for surgery and got Fentanyl & panadeine forte Antibiotic/Antiretroviral Drugs like Zyvox (linezolid) & Norvir (ritonavir) Dietary Supplements like St. John’s Wort & Ginseng Other Drugs That Affect Serotonin - Amphetamines - Cocaine and LSD and Mescaline https://www.drugs.com/npp/syrian-rue.html https://www.verywellmind.com/medications-and-serotonin-syndrome-2584342 However honestly with a good measure of caution and sense you should easily avoid most of these interactions. Oddly enough my interest in MAOI's are not is its psychotropic effects but rather things like Pancreatic islet cell proliferation. The more I read about harmala the more I would love to get it from my GP. For the moment I am just burning it as incense as a cleanser. The funny thing is that it is not a sweet smell like roses and sandalwood. Its more akin to really good BBQ - tempted to use it in the BBQ smoker. It also reminds me of the smell that a room gets from tobacco smoking. Not the tobacco smell but maybe its the harmala I am smelling. I am also very familiar with this Syrian Rue incense smell. I have encountered it many times up and down Sydney Road in Melbourne. Keeps the evil eye away. -
Syriab Rue/Ayahuasca & MAOI: Are the Dangers Real
Strontium Dawg replied to Ishmael Fleishman's topic in Pharmacology, Chemistry & Medicine
I was on some antidepressants in the 90s, didn't realize at the time that they were MAOI class, not SSRIs. I drank some ephedra tea and that sent me into 12 hours of the most intense migraine like headaches and nausea. And I imagine my trial was mild compared to what could have happened. At no point did the prescribing doctor tell me the medication was an MAOI or to watch my diet etc. I was well aware of MAOI interactions at this time, I just didn't make the connection with what happened to me until years later.
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