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The Corroboree
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A human test of high purity Honokiol (approx 80 - 90% Honokiol content) consumed via capsule ---- personally conducted by the creator of this site --- suggests that for a person of average weight (160 lbs), a dose of 3-4 grams is well-tolerated. At a dose as high as 8 grams, the side effect is limited to nausea ... which is frequently the case with cancer drugs.


The administrator of this site (160 lbs), who does not have cancer, has already established that 3-4 grams of high purity Honokiol (80-90%) taken orally once weekly is non-toxic, and that 8 grams caused nausea at worst.


It would seem logical, based on the lab test-results with mice, that if a solution of Honokiol were to be injected directly into cancer-infected tissue in a human being via a long needle, it might kill large areas of cancer cells locally. This approach would be similar to that taken with direct injection into tissue of rabies victims, though with a cancer patient several different areas may require this approach at the same time. Whether this would ultimately slow metastasis is unknown, at it has never been tried.


2004 also saw the release of a study from the Institute of Medical Sciences at Tzi Chi University demonstrating that Honokiol acted as an anti-seizure agent in lab animal tests, by acting as a "selective blocker of the NMDA receptor" in the brain.


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