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Ecstasy Deaths Linked To Raised Body Temperature

http://www.sciencedaily.com/releases/2008/...80531091527.htm 'A University of Adelaide study has revealed that effects of the drug ecstasy are compounded when taken in warm environments. Preclinical research undertaken by Pharmacology PhD student Emily Jaehne shows that ecstasy deaths, which are invariably related to elevated body temperature, may be related to drug users’ failure to recognise their body is abnormally hot. “The fact that these drugs are often taken in warm nightclubs and at r

Ed Dunkel

Ed Dunkel

Cops and robbers raid same house

http://www.ananova.com/news/story/sm_2871407.html ‘Two Australian burglars broke into a house - only to find it full of police officers staging a drugs raid. The pair jemmied open a window to get into the house in a midnight raid in Melbourne, reports the Herald Sun. But they had been beaten to it by police officers who had just burst through the door to search for drugs. The property was allegedly being used for growing hydroponic cannabis, and the detectives were on a raid to arrest the re

Ed Dunkel

Ed Dunkel

Stuff

Aquired a couple of new things the other day: Perovskia atriplicifolia 'Blue Spire' This stuff smells great! Can't wait to test the roots for activity, Salvia 'Blue Chiquita' This will probably turn out to be nothing spectacular. But no one seems to know what sp it actually is. Have tasted it: Leaves have a strange odour, like both officianalis and Pineapple sage at the same time. It is also fiercely bitter in a way that I have not tasted for a long time. Will post follow ups later;) Faucari

Yeti101

Yeti101

Chacruna

pictures taken in Peru...wonderful plant teacher...

mauve

mauve

Warning issued over unlicensed sex drugs

http://www.reuters.com/article/oddlyEnough...oddlyEnoughNews 'Canadians should avoid unlicensed drugs that claim to improve sexual performance because they could cause problems such as loss of consciousness, prolonged erections and chest pain, the health ministry said on Friday. Health Canada issued the warning in a release about a product called Desire, which was found to contain the prescription drug phentolamine -- something not indicated on the label. "Health Canada advises consumers not

Ed Dunkel

Ed Dunkel

Plectranthus

http://en.wikipedia.org/wiki/Plectranthus Plectranthus Neoclerodane and Labdane Diterpenoids from Plectranthus ornatus http://pubs.acs.org/cgi-bin/abstract.cgi/j.../np020203w.html Plectranthus: A review of ethnobotanical uses http://www.sciencedirect.com/science?_ob=A...09068c98d570b7b NAtive: Plectranthus graveolens or parviflora Plectranthus barbatus, contains forskolin graveolens and/or parviflora grows near me......

Yeti101

Yeti101

More potentials

Calamintha http://en.wikipedia.org/wiki/Calamintha I have no good evidence, except how the plants look.....

Yeti101

Yeti101

Sociology(Genealogy) of Entheobotanical exploration at a grassroots level.

I noticed that there seems to be much more effort (per head of community population) going into researching alternative (not currently in popular useage in the west) entheogens in Australian based communities such as the Coroborree, than there is at eDot or TheNook ( at least until recently). European enthnonbotay sites such as Psychonaut.com have virtually no knew research done by members. Now there are a number of viable explanations I'm sure. But here is what I think: Australia had Salvia

Yeti101

Yeti101

Candicine

Finally something kind of definitive on Candicine: "Nicotine-like action on the nervous system. In animals it provokes hypertension, while large doses have a curare-like action." Phytochemical Dictionary USe caution when consuming large amounts of T. spachianius. N, N, N-trimethyltyramine chloride - Starting to make sense now.

Yeti101

Yeti101

Notes on an argument against criminalisation

Notes on an argument against criminalisation What is the philosophical position of the TGA? Are they swayed by rational argument or only raw power? Determining these answers will provide direction in our way forward. How to combat the position that any drug other than the legal 3 (Alcohol, Tobacco and Pharmaceuticals) should be criminalised? Well that depends on what underlies that position. "If it's not broken don't fix it" conservatism - respond with 'but it is broken' "Drugs are danger

Yeti101

Yeti101

What can we actually do?

I'm wondering what it is (if anything) that I can do to change the legal status of certain plants, or at least halt the progression of criminalisation of others? can the TGA be lobbied? Can MP's do anything? Would they do anything? Even the Greens have stated that they do not support legalising any drug that is currently illegal. Should we make the TGA's job as difficult and costly as possible, within the bounds of the law of course - and then complain about the cost to the tax-payer? Maybe. Or

Yeti101

Yeti101

Is there an ethical problem with our community relying on animal studies?

Is there an ethical problem with our community relying on animal studies? Much , if not all, of the data I've dredged up lately has been based on animal testing, not all of it pleasant for the animals concerned. I'm generally against animal testing where it involves causing profound suffering and pain (note, not all animal testing does this) Furthermore animal testing can't really capture the subjective experience of a particular drug as we can't ask the mouse: "What was it like?" I'll leave t

Yeti101

Yeti101

School food laced with ecstasy

http://www.13wham.com/entertainment/weirdn...4b-a488924bd823 ‘Police in Russia are investigating after pupils stripped off their clothes, climbed walls or lay on the floor laughing after their school dinners were spiked with drugs. The teenaged students were given ecstasy in their soup and drinks at their school in the city of Yuzhno-Sakhalinsk in eastern Russia. Doctors who were called in said the students showed signs of intoxication and prosecutors later found traces of ecstasy.’

Ed Dunkel

Ed Dunkel

Can HGH Reverse Brain Damage in Drug Addicts?

http://www.sciam.com/article.cfm?id=can-hg...-dam&sc=rss 'Abuse of opiates such as heroin, methadone and morphine destroy brain cells, reducing attention span and memory. But new research shows there may be a way to regain some lost patience and recall. Researchers from Uppsala University in Sweden report in Proceedings of the National Academy of Sciences USA that brain cells targeted for early death by continued opiate use may be salvaged by injections of synthetic human growth hormone (H

Ed Dunkel

Ed Dunkel

Men charged after skull dug up, used as bong

http://www.reuters.com/article/oddlyEnough...oddlyEnoughNews 'Authorities in Texas have filed corpse-abuse charges against two men who allegedly removed a skull from a grave and used it as a bong. The Harris County District Attorney's Office confirmed on Thursday that misdemeanor abuse of corpse charges have been filed in the case. One of the men allegedly told police they dug up a grave in an abandoned cemetery in the woods, removed a head from a body and smoked marijuana using the skull as

Ed Dunkel

Ed Dunkel

Note to Self

No more obsessively scanning through electronic archives of other peoples work in search of exciting things! Quit living vicariously and go bioassay something yourself!

Yeti101

Yeti101

More Planta Medica Madness

"Pharmacological Investigation of Observed Anxiolytic Effects of the Marine Natural Product Aaptamine" Planta Medica 2008; 74 Aaptamine was administered in three doses (5, 10, 15 mg/kg i.m.) and the mice were observed for anxiolytic effects in an established chick social separation-stress model [3]. Results showed that separation-induced distress vocalizations were significantly attenuated in isolated chicks receiving 10 or 15 mg/kg aaptamine (ns = 12; ps < 0.05). However, higher concentrati

Yeti101

Yeti101

More potentials

Galphimia glauca - strong depressant activity on the nervous system http://0-www.thieme-connect.com.library.ne...5/s-2007-981539 "...important anxiolytic effectiveness, very similar to that produced with lorazepam...his compound exhibited an innovative action mechanism and selectively inhibited dopaminergic neurons discharges in the ventral tegmental area [16] without exhibiting interaction with the GABAergic system [17]." Planta Med 2007; 73: 713-717 Cistus creticus - sedative effects Mat

Yeti101

Yeti101

Stuff to chase up

Apocynum venetum http://0-www.thieme-connect.com.library.ne.../s-2008-1075172 Planta Med 2008; 74 DOI: 10.1055/s-2008-1075172 Anxiolytic Activity of Apocynum venetum L. and its Proposed Mechanism of Action O Grundmann1, J Nakajima2, V Butterweck1 1 College of Pharmacy, Department of Pharmaceutics,University of Florida, FL, 32610, USA 2 Tokiwa Phytochemical Co., Chiba 285–0801, Japan Apocynum venetum (AV, Apocynaceae) is a wild shrub native to parts of northern Asia and the Mediterranean

Yeti101

Yeti101

Kanna

Tried out my latest successful Kanna type thing. Equal portions of Sceletium tortuosum (mostly stemmy material), D cooperi (probably) and Aptenia cordifolia (leaves, stems and roots) were fermented in plastic bag in a warm place for about 7 days. After drying in the sun for some time, the process was finished by a quick roast in the oven at 150 C to ensure dryness & to get rid of any remaining oxalates. Inhaled a lot of the dust that came off when powdering/crushing. Ate a bit of stem (ple

Yeti101

Yeti101

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