Alchemica Posted May 9, 2017 Might be worth sourcing... Salvia aethiopis is a perennial plant native to Eurasia and known by the common names Mediterranean sage or African sage. This plant has been used in Iranian medicine as a carminative and tonic. The ethanolic extract of aerial part of S. aethiopis exhibited moderate to weak activity towards delta and kappa opioid receptors (46.3 and 45.3% displacement, respectively). Chromatographic purification of the ethanolic extract on silica gel column led to isolation of one new: 3α-hydroxy-8α-acetoxy-13,14,15,16-tetranorlabdan-12-oic acid (I) and three known compounds: sesquiterpene spathulenol (II), β-sitosterol (III) and β-sitosterol-3-O-glucoside (IV). The structures of all isolated compounds were elucidated by their NMR (1D and 2D) and MS spectral data. All the fractions and isolated compounds were tested for cannabinoid and opioid receptor binding assays. https://www.ncbi.nlm.nih.gov/pubmed/28475363 4 Share this post Link to post Share on other sites
inwould Posted June 9, 2017 (edited) Does the kappa opioid receptor activity suggest possible salvinorin-esque effects at certain doses? Edited June 9, 2017 by inwould Share this post Link to post Share on other sites
Yeti101 Posted June 11, 2017 How did I miss this? Very interesting. Share this post Link to post Share on other sites