Jack

African herb yields its anti-addiction secret 22 January 2005 From New Scientist Print Edition. THE secret of an African herb that helps drug addicts and alcoholics kick the habit has been discovered. The finding could lead to safer and more effective medications for treating addiction. Since the 1960s, many addicts have reported that even a single dose of ibogaine, a hallucinogenic alkaloid extracted from the root of an African shrub, helps them kick their habit by reducing their cravings for drugs. And there is hard evidence to back these claims, as well. However, troubling side effects - including heart problems and several deaths - have kept ibogaine from being widely accepted as a medical treatment. Instead, a few researchers have begun searching for ways to deliver ibogaine's benefits without its risks (New Scientist, 26 April 2003, p 34). A few previous studies have suggested that becoming addicted to a substance lowers the production of a nerve growth factor called glial cell-line derived neurotrophic factor, or GDNF. So Dorit Ron's team at the University of California, San Francisco, decided to test whether ibogaine affects GDNF levels in the brain. In rats injected with ibogaine, the researchers found that production of GDNF increased in a region of the brain called the ventral tegmental area. What's more, injecting either ibogaine or GDNF itself directly into this brain area decreased alcohol cravings in addicted rats, whereas injecting anti-GDNF antibodies eliminated any beneficial effect of ibogaine. The results appear in The Journal of Neuroscience. "The paper looks very solid," says Stanley Glick, a neuropharmacologist at Albany Medical Center in New York, who has studied ibogaine for many years. "They may indeed be on to a major finding." However, both Glick and Ron point out that boosting GDNF may be only one of several mechanisms by which ibogaine acts to ease addiction. A synthetic ibogaine compound, 18-methoxycoronaridine, which Glick has shown can help addicts with fewer harmful side effects than ibogaine, may also work by controlling GDNF levels. In preliminary studies with cultured nerve cells, Ron's team found that 18-MC also raises GDNF levels. But the team is not pursuing the ibogaine approach. Instead, Ron thinks it is time to narrow her focus. "Our idea now is to move away from ibogaine and concentrate on GDNF," she says. Her team plans to look for ways to stimulate GDNF without side effects. http://www.newscientist.com/article.ns?id=...=mg18524834.200 [ 21. January 2005, 09:02: Message edited by: Jack ]

Hi guys I have the following books available for sale: Eating the flowers of Paradise by Kevin Rushby (Hard cover) SOLD The narcotic officers notebook second edition By Malachi Harney & John Cross $10 Diary of a drug fiend by Alister Crowley $10 The coke book $10 Pharmako/Poeia by Dale Pendell $20 Marijuana Medical Papers Edited by Tod H Mukuriya MD (Signed) $30 The Psychedelic Explorer guide James Fadiman $20 Tripping edited by Charles Hayes $20 Pharmacotheon by Johnatha Ott $150 Ecstasy Dance Trance & Transformation by Nicholas Saunders $10 Marihuana Reconsidered by Lester Grinspoon $10 The Entheogen Review Volume IX 2,3 Volume X 1,2,3,4 Volume XI 1 (7 Issues) $25 Life Magazine March 25, 1966 LSD $20.00 Life Magazine September 9, 1966 LSD Art $20.00 Look Magazine August 8, 1967 Americas bad trip: the pot-and-pill kick that is getting out of hand $10 Thanks J

No it’s not a hard copy

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Where is the best place to buy bit coins from? THanks J

Does anyone know anything about this topic as i can find very little info online regarding this and cacti. So far my experiments are using mechanical injury to induce mutations will know more as these plants grow in the next 12months.

Updated list, adding old plants

The following plants are available for sale, PLants are seed grown and on own roots unless otherwise specified. All prices are plus postage. PM if interested.

TPM

Here it is Tipz, the original plant and the pup that I grafted I am hoping that it is going to crest as the areoles that are pupping look really strange..

Hey tipz I recieved a small pup from that crest which I won in your competition which I grafted, definately monstrose I'll post a photo soon.

THANKS

Hi looking for some Lophophora alberto-vojtechii plants PM me if you can help. Thanks J

In bali cant get anything exciting OTC, some pharmacy will sell you tramadol some times not, benzos definately not available OTC but sometimes you find pharmacys that wil sell you some valium (for me once in about 8 trips) but mostly not. Mushrooms are very strong over there, be careful. I couldnt find any stimulants..

Very good btw

Found growing near my usual sub patch. Thanks J

White spore print.. Tried some this morning with my eggs. Fried in oil with garlic and Tyme.. These have a really nutty flavour.. 3 hours on no reactions so far..

No spore print, will go back tomorrow.. are Chlorophyllum edible?

Philocacti can you show me a picture of the crested growth on your williamsii because in the photos above I dont see any crest.

Send me a pm I can help

Ive only chopped a hamilton peru crest and no air pockets..

http://www.kadasgarden.com/grafting3.html

All orders were payment was recieved by this morning are on there way.

Due to unforseen circumstances I am selling some of my personal collection, payment is by bank transfer or paypal by arrangement as you will need to pay any fees. PM me if interested in any of these plants. Please keep this topic as business only no chatter in order to keep it clean as i may decide to add more plants and dont want it cluttered. All prices are plus postage. I have only listed 1 Ario but may sell others if there is an interest please send me a message. Thanks and good luck

Is that garden in Moorabin?