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Solipsis

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About Solipsis

  • Rank
    Psychonaut

Contact Methods

  • Website URL
    zwonko.com

Profile Information

  • Country
    The Netherlands
  • Interests
    Experimenting with plants and fungi

Previous Fields

  • Climate or location
    Temperate

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  1. Solipsis

    Can people become immune to shrooms over time?

    Being on the spectrum is definitely not a guarantee or give a high chance of psychedelics not working as far as I know. (I am on the spectrum) Yes some are prescribed neuroleptics such as Seroquel which can block trips. However medication is not really that common for autism. However aside from that anyone can be naturally "immune" to either some psychedelics or all of them. Sensitivity to psychedelics is not associated with body weight like various drugs, but much more with CNS receptor populations like particularly 5-HT2A but also 5-HT1A among others and depending on the psychedelic. 2C-B for example is something of an exception with regard to the receptors it acts on. Anyway, IMO one of the best explanations for being "immune", highly insensitive to psychedelics or so-called hardheaded, is having polymorphism of these brain receptors. It means they are built and shaped slightly different and since the binding of drugs works a little like a lock and key this can mean that the psychedelic either cannot bind to the receptor or can bind but does not activate it at all, or does not activate it with the same effect. Because activating 1 receptor can have multiple different effects. It's not impossible that those with autism have a higher chance of having such polymorphism but I am not aware of evidence to suggest this besides very limited anecdotal. Tolerance is a much different topic but yes, when you take a psychedelic you tend to get a very fast and strong tolerance effect which makes you less sensitive to them for a while and that can mean even to other types of psychedelics than you took. Chronic tolerance can also mean that despite waiting in between trips, the tolerance can become exceedingly high over time and repeated tripping.
  2. Solipsis

    Edible/Medicinal culture seeking thread

    I don't wanna say that it is not harmful in any way, i don't know exactly. But the Alzheimer's concerns of aluminum have been debunked decades ago. Still, I def agree. It's just not nice to get a hole in your aluminum tray when you're growing. Get other trays or use a liner. You could save plastic trays you might buy meat in or other packagings of food items. Anyway, I would like to help you guys out with your requests as I have an extensive collection of fungi. But I do hail from the Netherlands so that can pose a problem. Could be worth trying tho and even retrying, esp with the right trade. I may accept the risk of seizure, depending. take care everyone.
  3. Solipsis

    Psilocybe cyanescens balcony planter

    Psilocybe cyanescens balcony planter
  4. Solipsis

    LW cristata

    LW cristata
  5. Echinopsis cv. Orange California x Clyde not entirely variegated
  6. Solipsis

    E. shaferii f. monstrose

    E. shaferii f. monstrose
  7. Solipsis

    LW Manchaca

    LW Manchaca
  8. Automated grow cabinet (not up to date)
  9. Loph W callus culture (meristem)
  10. Solipsis

    Lophophora TC

    Lophophora TC
  11. Solipsis

    fricii x fricii variegata

    fricii x fricii variegata
  12. Solipsis

    Micropropagation

    Micropropagation
  13. (TPM x Sharxx Blue) cristata - was reverted
  14. Solipsis

    Cactus TC

    Cactus TC
  15. Solipsis

    Echinopsis variegata

    Echinopsis variegata
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