Jump to content
The Corroboree

Leaderboard


Popular Content

Showing content with the highest reputation since 20/06/19 in all areas

  1. 6 points
    Howdy friends. Its been a long time coming, I've been a lurker here on and off for many years but never had an account. So here I am finally, able to actually communicate with those I have known for longer than most people in my life outside the internets. I don't post much but I am trying to get my garden back in order after moving around a lot so I'll be around the exchange a bit when there's interesting stuff going and I can share what I have. See you round the place.
  2. 4 points
    Hi, have 5 bags of ~ 50 seeds of N.rustica to share. Post below and PM me your details to recieve a pack. Kindness H
  3. 4 points
    Dear community, In the interest of furthering the knowledge base relating to propagation and viability of various Acacia Sp. (particularly in the harsh climate of southern Tasmania) I have prepared a short video clip which I believe covers a lot of the information that was a little hard to find several years ago when I started out in this area. If anyone can offer any words of improvement or constructive criticism they will be gladly accepted. I hope you find it entertaining and useful. Below and linked here as well: https://drive.google.com/open?id=1e9AuVqdQpJnYlnsjRx7LZFYi9gqvf4xG 300619_Growing_Acacias_in_Southern_Australia.mp4
  4. 4 points
    Just because it's such a beautiful plant and many members here seek to grow it... I thought I'd let all you good folks here know that EntheoBotanica have seed in stock at the moment at a fantastic price and I'd love to see as many people growing it as possible (so don't be too greedy and buy them all ...just get enough seeds so that every one can grow a few healthy seedlings and eventually trees). https://www.entheo-botanica.org/product-page/acacia-courtii-seed-nsw-northern-three-brother-wattle
  5. 4 points
    Thanks for sharing, that was an interesting read. Ill kick start the discussion by sharing a few thoughts I had while reading the paper. In situ hybridization isn’t the best technique to demonstrate DMT is produced within brain tissues. In situ hybridization allows for visualization of mRNA. Ok so now we know INMT and AADC mRNA has been detected within these tissues. But do we know if INMT and AADC mRNA completes to process of translation to produce functional enzymes? They make a big deal in this study about being the first time to demonstrate INMT and AADC mRNA co-localise within the same cells. But this isn’t the important factor, the important factor is does translation occur allowing both enzymes to function within the same cell? I feel this paper would have been strengthened by examining the protein/enzyme levels not just the mRNA level. Secondly demonstrating the required enzymes mRNA exist in mice and human brain tissues, but only demonstrating the detection of DMT within mice tissues and not human tissues further weakens this publication. If they have the human brain tissues to perform in situ hybridization on, why not perform HPLC as well? Or maybe they did but didn’t publish the results because it didn’t confirm their hypothesis? This would be important data to publish because without it they are relying upon the assumption that INMT and AADC exclusively function to produce DMT when in reality they could perform their function upon a vast number of additional substrates that do not contribute to the DMT biosynthetic pathway. And finally, its amazing to think they have developed mice without pineal glands, and quite interesting that the mice with and without pineal glands produced statistically similar concentrations of DMT. Regardless of my minor criticisms it’s an interesting read and I hope this group gains additional funding, so they can continue their work in the future.
  6. 4 points
    Hey Sydney folks - Mushroom Day THIS SUNDAY !!! Don't miss out on tickets they're selling fast and this promises to be our biggest event yet https://events.humanitix.com.au/mushroom-day-with-aps-sydney
  7. 4 points
    Wait... there's a specific mushroom day? I thought every day was mushroom day...?
  8. 3 points
    Welcome. I greet you in the Love and Light. I’m giving away free seed packs of Datura stramonium (approx 10x seeds). The first 5x people to post on here will be the lucky recipients. Please send me a PM with the details of where you would like it posted. For incense use only. Love & Light ∞
  9. 3 points
    Please don't mistake "freedom of speech" with "freedom from consequences". He signed a legal contract willingly, then deliberately broke the terms of the contract even though he had been given warning so I fail to see how this is even relevant. If he didn't like the terms of the contract he signed he shouldn't have signed it and made millions of dollars for chasing a ball around a field.
  10. 3 points
    https://www.theguardian.com/global-development/2019/jun/26/illegal-drugs-classifications-based-on-politics-not-science-cannabis-report-says Illegal drugs including cocaine, heroin and cannabis should be reclassified to reflect a scientific assessment of harm, according to a report by the Global Commission on Drug Policy. The commission, which includes 14 former heads of states from countries such as Colombia, Mexico, Portugal and New Zealand, said the international classification system underpinning drug control is “biased and inconsistent”. No shit...
  11. 3 points
  12. 2 points
    https://www.jofsr.org/index.php/path/article/view/30/21 this study hypothesizes that bees can literally see and may also be attracted to harmala alkaloids, with plants using them as pollination signals also contains some interesting testing on abundance & variety of harmala type alkaloids within a variety of plants - anybody got some Thalictrum aquilegiifolium seeds? edit: i might put some p. harmala seed out in the garden and see if the bees find it interesting at all hahaha
  13. 2 points
    A recent summary is online with more to come. https://cactusconservation.org/blog/2019/05/17/lophophora-williamsii-harvesting-regrowth-mortality/
  14. 2 points
    Aromatherapy vs oral oils Orally essential oils seem to be reliant on pharmacological effect but aromatherapy seems to be more overlapped with socio-emotional states of consciousness and a way to ingrain some mindfulness: Olfaction is intimately related to social communication and emotions Scent playlists have been proposed It's like a very gentle, non-threatening catalyst for stuck and stagnant negative thought patterns and emotions. The longer you sit with the fragrant stream aligning your body-mind-spirit, the more there is a gentle unwinding of rigid patterns, deeper embrace of yourself and a gentle positive merger with the world around you It gives you: - a sense of control over your environment - you choose what's diffusing - even when you feel life's out of control. A safe "grounding" base - a sense of connection: to the moment and to the world around you. Deepens your connection to yourself (and nature) - ingrains simple breathing as a positive mindful experience/makes you more aware of it, attunes you to deeper layers of yourself -particularly emotions - and to a connection in the world beyond you - a spiritual element - environmental enrichment with ability to tap into socio-emotional-spiritual aspects - ability to shift the valence of the emotional landscape to more positive experiences along with emotional exploration and reminiscence. Ability to shift thoughts in line with the emotions - As studies have noted, nocturnal olfactory stimulation leads to better sleep quality and a higher level of vigor in the morning "Odour can colour perceptions about the world both positively or negatively through emotion processes and thus can modulate mood and behaviour" Effects of inhaled essential oils cannot be explained by pharmacological mechanisms alone. "Olfaction is intimately linked to emotional processes, sharing some same neural bases and thus constitutes a valuable emotion-inducer" [1]. Expectancies play an important role in the subjective effects of inhaled EOs [2]. Odour pleasantness selectively shifts human attention in the surrounding space [3] and modulates the hedonic value of rewards [4] In monotonous situations it improved mood and other measures [5] Odours that evoke positive autobiographical memories being able to increase positive emotions, decrease negative mood states, disrupt cravings, and reduce physiological indices of stress, including systemic markers of inflammation [6] Odour may serve as a powerful cue for the recovery of autobiographical memories, inducing subjective reliving and more positive memories after odour exposure [7] producing a number of and more specific memories after odour exposure than without odour [8]. Beneficial effects of same nature to odour and music exposure were observed for autobiographical characteristics (i.e., specificity, emotional experience, and mental time travel) [9] [1] https://www.ncbi.nlm.nih.gov/pubmed/27633559 [2] https://www.ncbi.nlm.nih.gov/pubmed/25183507 [3] https://www.ncbi.nlm.nih.gov/pubmed/28872341 [4] https://www.ncbi.nlm.nih.gov/pubmed/25543090 [5] https://www.ncbi.nlm.nih.gov/pubmed/27633559 [6] https://www.ncbi.nlm.nih.gov/pubmed/27447673 [7] https://www.ncbi.nlm.nih.gov/pubmed/31185649 [8] https://www.ncbi.nlm.nih.gov/pubmed/30890017 [9] https://www.ncbi.nlm.nih.gov/pubmed/29040475
  15. 2 points
    Thanks for the responses everyone, Maybe I will write them an email, but I should probably spend a little more time reading their previous publications first to gain a greater perspective of their past work. Perhaps a lot of my questions have already been answered in past publications, and I wouldn’t want to waste their time repeating themselves. The whole subject is so fascinating, which gets my brain ticking with a lot of questions. So if the theory is, DMT is produced at death, my focus turns to, how can that be regulated? If it wasn’t regulated people would randomly be experiencing this state of mind all the time and perhaps a small percentage of people already do. But if we understood how it was regulated, maybe we could manipulate this level of regulation to induce this phenomena without the need to induce cardiac arrest. Considering if it (DMT produced at death) exists, it must be regulated, leds to several hypothesis including (1) does some sort of signalling molecule trigger the transcription of these enzymes when near death states are being experienced? Allowing for DMT biosynthesis to occur, Or (2) are these enzymes already present but an inhibitor molecule prevents there action, then in times of near death states, a signalling molecule triggers the breakdown of the inhibitor allowing the enzymes to function. If the first is occurring, then its amazing that our bodies can detect imminent death and have the time to produced enzymes, then time for the enzymes to function, allowing for biosynthesis to occur. For this reason, the second hypothesis makes more sense because I assume transcription and translation would be wasting valuable time when your seconds away from kicking the bucket. However, I am not sure how to determine how long these processes actually take to occur. Then again, maybe im way off the mark and its regulated by a completely different mechanism, or maybe this phenomena doesn’t even exist. Either way it’s fun to think about.
  16. 2 points
    Been getting the aromatherapy into me, rather than ingesting. I was in the past fixated on oral ingestion being 'the way to go therapeutically' for things like lavender but I've often wondered if it really is... More and more people seem to be using the Silexan oral oils, particularly now they are widespread at Australian chemists, have you had any experience, good or bad with them, particularly compared to lavender as aromatherapy? Aroma via a diffuser has lately been a important aspect to enrich my environment with day-to-day, without those it becomes too easy to get lost in the void of your own inner world without things like that stimulating you via the environment in isolation as some form of modulating connection to the world around you, in the moment, with a degree of impermanence and day-to-day flux "Aromatherapy seems to drive autonomic nervous activity toward a balanced state." In anxiety and stress, sympathetic activity is often increased, together with decreased parasympathetic activity. It has been noted there are higher sympathetic activities for depressed and anxious subjects than for normal subjects:"Positive emotions result in altered autonomic nervous system activity, characterized by increased parasympathetic nervous system activity, whereas negative emotions (e.g., anger) result in parasympathetic withdrawal and sympathetic activity" It is said there are parasympathetic-stimulating oils like lavender and the sympathetic-stimulating oils like rosemary but a study has noted that short inhalation of essential oils suppresses parasympathetic nervous activation while continuous inhalation suppresses sympathetic nervous activation [1] Oils that cause parasympathetic stimulation of the autonomic nervous system in turn are associated with decreased anxiety, improved mood, and increased sedation whereas the sympathetic-stimulating oils have been associated with increased arousal, improved cognition and memory, and enhanced performance on cognitive assessment tests [2] Essential oil inhalation is often effective in reducing the stress index, and that it effectively regulated the activity of the hypothalamus to provide stable and relaxing conditions by creating balance and harmony in the sympathetic nervous system "A clinical study with depressed patients revealed that it was possible to reduce the needed antidepressants' doses by inhaling a mixture of citrus oils; moreover, inhalation of the oil by itself was antidepressive and normalized neuroendocrine hormone levels" [3] With regard to agitation and anxiety, in a clinical mental health population, there were significant reductions in needed medications for anxiety or agitation With regard to depression, significantly more improvement in scores on depression, anxiety, and severity of emotional symptoms, studies finding effects independent of personality traits, psychological status, and psychotherapeutic medication [1] https://www.researchgate.net/publication/288053919_Effects_of_essential_oils_used_in_aromatherapy_on_the_autonomic_nervous_system_A_study_using_three_different_methods [2] https://libres.uncg.edu/ir/uncg/f/M_Shattell_HealingScents_2008.pdf [3] https://www.mitchmedical.us/essential-oils/psychopharmacology-of-essential-oils.html Lavender is rising through the ranks of anti-anxiety medications Lavender oil and its active component, linalool, has anxiolytic, mood stabiliser, sedative, analgesic, and anticonvulsive and neuroprotective properties with antidepressant, prosocial and anticonflict effects in animal models It shows efficacy in anxiety disorders and the treatment of agitated behaviour as a neuropsychiatric symptom [1] Simple olfactory stimulation in healthy subjects has been shown to induce changes in brain including the frontopolar, orbitofrontal, and temporal cortex. Olfactory processing depends on dopamine metabolism and orbitofrontal cortex functioning and altering cortical olfactory processing has been associated with improved hyperactivity and impulsivity in some conditions [2] and essential oils may rehabilitate brain dopamine function [3]. There is sensory input-dependent regulation of dopamine and GABA [4] The effect on the nervous system is summarised in [5]: Inhaled it showed anxiolytic properties, increased social interaction, and decreased aggressive behaviour and exposure to lavender effectively improved anticholinergic-induced memory deficits It has potent anxiolytic effects via VDCCs and while linalool does not act directly on GABAA receptors it appears to activate them via olfactory neurons in the nose in order to produce its relaxing effects [6]. While opioidergic neurotransmission and cholinergic neurotransmers appears to play a role, the essential oil and its main components exert affinity for the glutamate NMDA-receptor in a dose-dependent manner and also bind to the serotonin transporter. After 8 weeks of administering the essential oil, a reduced binding potential at the 5HT1A receptor in the hippocampus and the anterior cingulate cortex has been observed It affects autonomic neurotransmission and reduces the stress response in the CNS. In one study the concentration of oxytocin in serum, 2-3 days after the treatment was upregulated with effects on improved neurogenesis and dendritic complexity [7]. It also acts on microglial populations with anti-inflammatory actions "...stress-altered genes involved in synaptic transmission via GABA, dopamine, acetylcholine, and glutamate may potentially recover to normal levels due to a reduction in stress in response to linalool inhalation". It was capable of reversing stress-induced social aversion in animal models, acting as an antidepressant agent [8]. Application of 10% lavender in humans activated the primary olfactory cortex, entorhinal cortex, hippocampus and parahippocampal cortex, thalamus, hypothalamus, orbitofrontal cortex, and insular cortex and its extension into the inferior lateral frontal region [1] https://www.ncbi.nlm.nih.gov/pubmed/11994882 [2] https://www.ncbi.nlm.nih.gov/pubmed/21178380 [3] https://www.ncbi.nlm.nih.gov/pubmed/26295793 [4] https://www.ncbi.nlm.nih.gov/pubmed/28411275 [5] https://www.ncbi.nlm.nih.gov/pubmed/23573142 [6] https://www.sciencedaily.com/releases/2018/10/181023085648.htm [7] https://www.ncbi.nlm.nih.gov/pubmed/30825591 [8] https://www.ncbi.nlm.nih.gov/pubmed/30347669 Tried things like Lemon and Rosemary as a stimulating option Terpenes seem to work as a symphony with seemingly synergistic effects to me when you really inhale a good stream of them. A bit of a linalool oil is good but... it's better with a bit of limonene in there... even better with α-pinene rich oils etc The polytherapeutic effects of natural compounds are a "are a real alternative for nervous system therapy" [1] Rosemary essential oil is a "powerful tool in helping to clear the mind and for increasing mental awareness. It has also been shown to possess excellent brain-stimulating properties as well as an aid for memory improvement". It made humans more attentive, more alert, vigorous and cheerful [2] and people "felt fresher, became more active, and less drowsy after exposure to the rosemary oil". It also produces a significant enhancement in memory performance and mood [3. 4]. Inhaling lemon essential oil causes antidepressant and anti-stress effects through modulating monoamines and significantly enhanced attention level, concentration, cognitive performance, mood, and memory during the learning process [5] The chemistry: α-Pinene and 1,8-cineole generally dominate the Rosemary essential oil compositions, but camphor, verbenone, camphene, and myrcene may also appear in high concentrations [6] Pharmacology: α-pinene [(+)-α-Pinene was the predominant enantiomer] and 1,8-cineole are potent therapeutics. Performance on cognitive tasks is significantly related to concentration of absorbed 1,8-cineole following exposure to rosemary aroma, with improved performance at higher concentrations [7] 1,8-cineole offers NMDA antagonism, with a weaker AChE inhibitory effect [8] and psychostimulatory effects, anti-inflammatory and antioxidant effects [9] α-Pinene brings along effects on learning and memory [10] with anti-stress effects, also modulating NGF and dopamine [11] Monoterpenes such as α-pinene and 1,8-cineole exert neuroprotective effects by regulating gene expression and α-pinene was observed to initiate soothing physiological and behavioural responses with a significant impact on physiological and psychological relaxation [12]. Citrus oils have their pharmacology well sumarised in [5] [1] https://www.ncbi.nlm.nih.gov/pubmed/30378477 [2] https://www.mdpi.com/2218-0532/77/2/375 [3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700080/ [4] https://www.ncbi.nlm.nih.gov/pubmed/12690999 [5] https://www.ncbi.nlm.nih.gov/pubmed/29976894 [6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368539/ [7] https://www.ncbi.nlm.nih.gov/pubmed/23983963 [8] https://www.ncbi.nlm.nih.gov/pubmed/28088901 [9] https://www.ncbi.nlm.nih.gov/pubmed/27771935 [10] https://www.ncbi.nlm.nih.gov/pubmed/29234406 [11] https://www.ncbi.nlm.nih.gov/pubmed/29273038 [12] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402865/ Spanish sage: Spanish sage is proposed to be an "excellent essential oil to diffuse when concentrating" and "For soothing anxiety, tension and stress" Salvia lavandulaefolia aroma inhalation produced a significant enhancement effect for memory [1] and orally at 50 µL of the essential oil, improvement in mood and cognition was observed [2] - therapeutic effect for cognitive disorders attributed to its anti-cholinesterase, estrogenic, and anti-inflammatory properties - potential natural antioxidant activity to prevent oxidative stress accompanying degenerative diseases Enjoying a blend of Spanish Sage, Lavender and Lemon (all on the "blends well with..." list on one site) like the Rosemary blends, similarly to which it brings along 1,8-cineole and α-pinene. I also notice that having scent as an enriching environmental stimulus stops the desire to generally snack on anything and there is a role for scent in modulating blood glucose [3] [1] http://dx.doi.org/10.4236/aces.2014.43037 [2] https://doi.org/10.1177/0269881110385594 [3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820856/
  17. 2 points
    I'm not. Fukd shit is fukd. I stand by my statement, harsh as it is.
  18. 2 points
    A lot of laws are pretty stupid but the human rights have been thought out pretty well. While this fella is getting paid millions to chase a ball around. I work with a lot of children and families who are dealing with child suicide. Try and imagine a 14 year old boy who just happens to of been born gay. Now this hypothetical boy was also born into a strict christian family. Mate I find all this superstition bizarre, yet there are a lot of people who take all this heaven and hell stuff seriously. Now imagine this boys biggest hero is some meathead footballer who doesn't have enough grey matter to know when to keep his bigotry to him self. Do you see where I am going? This sort of shit is incredibly common. Personally think sports people as role modals is just asking for trouble.
  19. 2 points
    ^ One good thing about capitalism I guess. It can get stuff done. I think in that circumstance as long as the average person can benefit from it, by being able to create a business it’s a good thing. It’ll be a bad thing if you need expensive licenses that only big business can afford... ——————— https://www.smh.com.au/national/uniting-church-and-alan-jones-back-legal-push-to-decriminalise-ice-use-20190626-p521jh.html scare mongering in the title, but actually for use of all drugs. From the church and alan Jones? Lol what
  20. 2 points
  21. 2 points
    well 9-20 is actually now the official Psilocybe Mushroom Day (rather Amero-centric though)... but we're doing it late June in Sydney coz its the peak of season here https://www.vice.com/en_us/article/avaej4/can-920-become-the-420-of-magic-mushrooms
  22. 2 points
    This is Leratiomyces ceres.
  23. 2 points
    https://www.telegraph.co.uk/news/2019/06/20/france-urged-government-experts-legalise-cannabis-take-back/ --- In their report released on Thursday entitled “Cannabis: how to take back control”, the two CEA-mandated economists wrote: “The system of prohibition promised by France for the past 50 years has been a failure. ”State-controlled cannabis stores would be the best way to control drug trafficking and “restrict access” to younger would-be users, they argued. "By their calculations, cannabis could bring up to €2.8 billion (£2.5bn) per year into state coffers and create up to 57,000 jobs."--- So really, it's about the $$. Are we heading in the right direction for the wrong reasons. And if we are, what will be the consequences?
  24. 2 points
    Heading down? I think the 'heading' has been going on for some time now...
  25. 2 points
    NZ government already going back on the promise to have a binding referendum. https://www.adelaidenow.com.au/news/world/nz-govt-unveils-details-of-recreational-cannabis-referendum/video/a1f1d4062a31c3e707c13b0e74b6987f
×